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논문 기본 정보

자료유형
학술저널
저자정보
Bigyan B. Mainali (Department of General Surgery, Atrium Health Wake Forest Baptist) Yoo James J. (Wake Forest Institute for Regenerative Medicine, Wake Forest School of Medicine) Mitchell R. Ladd (Department of Biomedical Engineering, Wake Forest University)
저널정보
대한대장항문학회 Annals of Coloproctology Annals of Coloproctolgy 제40권 제4호
발행연도
2024.8
수록면
336 - 349 (14page)
DOI
10.3393/ac.2024.00437.0062

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Tissue engineering and regenerative medicine (TERM) is an emerging field that has provided new therapeutic opportunities by delivering innovative solutions. The development of nontraditional therapies for previously unsolvable diseases and conditions has brought hope and excitement to countless individuals globally. Many regenerative medicine therapies have been developed and delivered to patients clinically. The technology platforms developed in regenerative medicine have been expanded to various medical areas; however, their applications in colorectal surgery remain limited. Applying TERM technologies to engineer biological tissue and organ substitutes may address the current therapeutic challenges and overcome some complications in colorectal surgery, such as inflammatory bowel diseases, short bowel syndrome, and diseases of motility and neuromuscular function. This review provides a comprehensive overview of TERM applications in colorectal surgery, highlighting the current state of the art, including preclinical and clinical studies, current challenges, and future perspectives. This article synthesizes the latest findings, providing a valuable resource for clinicians and researchers aiming to integrate TERM into colorectal surgical practice.

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