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논문 기본 정보

자료유형
학술저널
저자정보
Pornsirirat Thonnarat (Siriraj Hospital, Mahidol University) Kasemvilawan Nualnapa (Siriraj Hospital, Mahidol University) Pattanacharoenwong Patcharavalia (Siriraj Hospital, Mahidol University) Arpibanwana Saisunee (Siriraj Hospital, Mahidol University) Kondon Hatairat (Siriraj Hospital, Mahidol University) Naorungroj Thummaporn (Siriraj Hospital, Mahidol University)
저널정보
대한중환자의학회 Acute and Critical Care Acute and Critical Care Vol.39 No.3
발행연도
2024.8
수록면
379 - 389 (11page)
DOI
10.4266/acc.2024.00038

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Background: Hypothermia is a relatively common complication in patients receiving continuous renal replacement therapy (CRRT). However, few studies have reported the factors associated with hypothermia.Methods: A retrospective cohort study was performed in five intensive care units (ICUs) to evaluate the incidence of hypothermia and the predictive factors for developing hypothermia during CRRT, with hypothermia defined as a time-weighted average temperature <36 °C.Results: From January 2020 to December 2021, 300 patients were enrolled. Hypothermia developed in 23.7% of them within the first 24 hours after CRRT initiation. Compared to non-hypothermic patients, hypothermic patients were older and had lower body weight, more frequent acidemia, and higher ICU and 30-day mortality rates. In the multivariate analysis, age >70 years (odds ratio [OR], 2.59; 95% CI, 1.38–4.98; P=0.004), higher positive fluid balance on the day before CRRT (OR, 1.11; 95% CI, 1.02–1.22; P=0.02), and CRRT dose (OR, 1.003; 95% CI, 1.00–1.01; P=0.04) were significantly associated with hypothermia. Conversely, a higher body weight was independently associated with mitigated risk of hypothermia (OR, 0.89; 95% CI, 0.81–0.97; P=0.01). Moreover, a higher coefficient of variance of temperature was associated with greater ICU mortality (OR, 1.41; 95% CI, 1.13–1.78; P=0.003).Conclusion: Hypothermia during CRRT is a relatively common occurrence, and factors associated with hypothermia onset in the first 24 hours include older age, lower body weight, higher positive fluid balance on the day before CRRT, and higher CRRT dose. Greater temperature variability was associated with increased ICU mortality.

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