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논문 기본 정보

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학술저널
저자정보
Denis Jevdokimov (Center of Gastroenterology, Hepatology and Nutrition, Pauls Stradins Clinical University Hospital, Riga, Latvia) Natalija Jevdokimova (Center of Gastroenterology, Hepatology and Nutrition, Pauls Stradins Clinical University Hospital, Riga, Latvia) Aldis Pukitis (Center of Gastroenterology, Hepatology and Nutrition, Pauls Stradins Clinical University Hospital, Riga, Latvia)
저널정보
소화기인터벤션의학회 International Journal of Gastrointestinal Intervention International Journal of Gastrointestinal Intervention Vol.13 No.3
발행연도
2024.7
수록면
86 - 90 (5page)
DOI
https://doi.org/10.18528/ijgii240018

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Background: Endoscopic retrograde cholangiopancreatography (ERCP) is a minimally invasive endoscopic method that is used for the diagnosis and treatment of pancreaticobiliary diseases. ERCP may have to be performed two or more times, which carries a risk of complications and even death. Various risk factors influence the likelihood of ERCP recurrence. Methods: A retrospective study was conducted at Pauls Stradins Clinical University Hospital. Fifty patients with a history of repeat ERCP were enrolled. The total ERCP count was 122. The total death rate, 30-day postprocedural mortality, laboratory markers, and primary diagnosis were analyzed, and the therapeutic interventions used during ERCP, common bile duct’s diameter, and causes of repeat ERCP were evaluated. Results: The postprocedural 30-day mortality of repeat ERCP was 3.3%, and the overall death rate was 8%. We found a significant difference between the number of repeat ERCPs and exitus letalis (mean = 2.25 vs. mean = 1.37). The most common primary diagnosis for repeat ERCP was choledocholithiasis (64%; n = 32). We found a significant relationship between choledocholithiasis and history of cholecystectomy (P < 0.001) and obesity (P < 0.001). The rate of successful cannulation for ERCP reached 88.5%, with a significant difference between the success of cannulation and bilirubin level (205.64 ± 234.42 μmol/L vs. 58.71 ± 97.65 μmol/L, P = 0.037). The results showed a significant relationship between the success of cannulation and the presence of jaundice (P = 0.014) and periampullary diverticulum (P = 0.017). Conclusion: A greater number of repeated ERCPs carries a higher risk of overall death outcome. The disturbances in laboratory markers (decreased hemoglobin; elevated leucocytes, bilirubin, creatinine, alkaline phosphatase, C-reactive protein) could be a risk factor for negative 30-day postprocedural outcome. The risk factors for repeating ERCP include adiposity, history of cholecystectomy, bilirubin level, jaundice, and periampullary diverticulum.

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