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Anti-acne and Tolerance Assessment of a Cleanser Containing Salicylic acid, Gluconolactone and Niacinamide
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Type
Academic journal
Author
Yu Cao (Dermatology Center, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China) Yunfei Ai (L'Oréal (China) Co., Ltd., Shanghai, China)
Journal
한국피부과학연구원 아시안뷰티화장품학술지 아시안뷰티화장품학술지 제22권 제3호 KCI Accredited Journals
Published
2024.9
Pages
383 - 391 (9page)

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Anti-acne and Tolerance Assessment of a Cleanser Containing Salicylic acid, Gluconolactone and Niacinamide
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Purpose: Acne has potential to cause psychological distress and significantly diminish one's quality of life. Although washing and over-the-counter cleansers are commonly used in the treatment of acne vulgaris, clinical evidence supporting their effectiveness is still limited. The main focus of this research is to explore anti-acne effectiveness and mildness of a cleanser containing salicylic acid, gluconolactone, and niacinamide. Methods: We recruited two groups of participants. One group consisted of 43 individuals with oily acne-prone skin, and we measured their inflammatory lesions, non-inflammatory lesions, and sebum content after 4 weeks of product usage. The other group included 39 individuals with sensitive skin, and we assessed objective irritation parameters and subjective irritation parameters after 2 weeks’ product usage. Results: After 4 weeks of using cleanser containing retinol, niacinamide and ceramides on oily acne-prone skin, significant reductions were observed in both inflammatory acne lesions count and non-inflammatory acne lesions count, while there was also a significant decrease in skin sebum content. After two weeks of use on sensitive skin, significant improvements were observed in both subjective and objective irritation parameters. Conclusion: In summary, a cleanser containing salicylic acid, gluconolactone and niacinamide can effectively improve acne symptoms while being gentle enough for use on sensitive skin.
#Cleanser #Acne #Sensitive skin #Salicylic acid #Niacinamide

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