The purposes of this study were to investigate relationships between daytime sleepiness, insomnia, and the quality of sleep in clinical nurses and provide basic data for the development of effective interventions for increasing the quality of sleep. The subjects included 208 nurses from five general hospitals in the J province. Data were collected with a self-reported questionnaire on May, 2014. Pittsburgh Sleep Quality Index(PSQI), Korean Epworth Sleepiness Scale(KESS), Insomnia Severity Index(ISS) were employed in this study to measure the quality of sleep, daytime sleepiness and insomnia. The data were analyzed using Cronbach''s α, descriptive statistical analysis, t-test, ANOVA, Scheffe''s test, Pearson''s correlation coefficient, and multiple regression analysis with the SPSS 20.0 version program. The result of this were as follows: 1. The mean scores of the subjects were 7.58(±3.61) on daytimesleepiness, 9.93(±6.22) on insomnia, and 7.29(±3.05) on the quality of sleep. 2. The differences in daytime sleepiness, insomnia, and the quality of sleep according to general characteristics, health-related characteristics, and job-related characteristics were as follows: 1) There were significant differences in daytime sleepiness according to age group, marital status, having worries, perceived stress, depression, alcohol consumption, clinical experience, clinical experience in present department, position, shift work, the number of night shifts in a month, physical working burden, work satisfaction, and fit to the job. 2) There were significant differences in insomnia according to age group, educational level, marital status, leisure time, having worries, perceived stress, depression, alcohol consumption, subjective health status, clinical experience), clinical experience in present hospital, position, shift work, clinical experience in shift, the number of night shifts in a month, physical working burden, work satisfaction, and fit to the job. 3) There were significant differences in the quality of sleep according to age group, educational level, marital status, leisure time, having worries, perceived stress, depression, alcohol consumption, subjective health status, clinical experience, clinical experience in present hospital, working unit, shift work, the number of night shifts in a month, physical working burden, work satisfaction, and fit to the job. 3. The daytime sleepiness had significant positive correlations with insomnia(r=.49, p<.001) and the quality of sleep(r=.50, p<.001). And insomnia had significant positive correlations with the quality of sleep(r=.72, p<.001).4. The quality of sleep in clinical nurses significantly influenced by insomnia(β=0.55, t=8.14, p<.001), daytime sleepiness(β=0.16, t=2.83, p=.005), and work satisfaction(β=-0.15, t=-2.35, p=.020). The three variables explained 55.9% of variance of the quality of sleep(F=10.73, p<.001). For the generalization of these findings, the nurses in various hospitals considered the size and working environment should be studied. To Improve the quality of sleep, the way to enhance daytime sleepiness and insomnia should be considered, for those who were in their twenties, were single, had clinical experience of 5-10 years, and were shift workers.