지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학위논문
- 저자정보
- 지도교수
- 이진춘
- 발행연도
- 2017
- 저작권
- 부산대학교 논문은 저작권에 의해 보호받습니다.
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Background and Objectives
The aims of this study were to evaluate the rate and risk factors involved in bilateral central lymph node metastasis in patients with papillary thyroid cancer (PTC) located in the isthmus compared to tumors located in other thyroid regions, and to use those findings to establish a surgical strategy for treating these tumors.
Subjects and Method
We compared the clinical and pathological data of 48 patients with isthmic PTC and 141 patients with PTC located in other thyroid regions, all of whom underwent total thyroidectomy and bilateral central neck dissection.
Results
The rates of bilateral central lymph node metastasis were higher in the isthmus group than the nonisthmus group (29.2% vs 9.9%; p = .001). On multivariate analysis, isthmic location of the tumor was an independent risk factor for bilateral central lymph node metastasis (OR = 3.458; p = .005). But, the positional relationship between the tracheal midline and the nodule was not clear in lymph node metastasis in the isthmus group.
Conclusion
Bilateral central neck dissection should be considered for isthmic PTC regardless of the relation between nodule and tracheal midline because of the high rate of bilateral central lymph node metastasis.
The aims of this study were to evaluate the rate and risk factors involved in bilateral central lymph node metastasis in patients with papillary thyroid cancer (PTC) located in the isthmus compared to tumors located in other thyroid regions, and to use those findings to establish a surgical strategy for treating these tumors.
Subjects and Method
We compared the clinical and pathological data of 48 patients with isthmic PTC and 141 patients with PTC located in other thyroid regions, all of whom underwent total thyroidectomy and bilateral central neck dissection.
Results
The rates of bilateral central lymph node metastasis were higher in the isthmus group than the nonisthmus group (29.2% vs 9.9%; p = .001). On multivariate analysis, isthmic location of the tumor was an independent risk factor for bilateral central lymph node metastasis (OR = 3.458; p = .005). But, the positional relationship between the tracheal midline and the nodule was not clear in lymph node metastasis in the isthmus group.
Conclusion
Bilateral central neck dissection should be considered for isthmic PTC regardless of the relation between nodule and tracheal midline because of the high rate of bilateral central lymph node metastasis.
목차
1. 서론 22. 대상 및 방법 53. 결과 84. 고찰 125. 결론 186. 참고문헌 197. 표 및 그림 238. 영문요약 31
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