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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 1999.6
- 수록면
- 259 - 262 (4page)
이용수
초록· 키워드
오류제보하기
Local irritation of YHB6211, a recombinant human granulocyte-colony stimulating factor, was assessed in male New Zealand White (NZW) rabbits by dermal and ocular application. In the skin irritation test, 0.5 ml of 0.03% YHB6211 aqueous solution was applied to the back skin of rabbits for 24 hours, and subsequent observation was performed. The solution did not induce any response after the treatment, and the primary irritation index (P.I.I.) of the compound was 0. In the eye irritation test, 0.1 ml of the same solution was instilled into the conjunctiva of the eye. No treatment related reactions were observed at the cornea, iris, and conjunctiva. Based on these results, 0.03% (w/v) YHB6211 solution could be considered as a non-irritating material.
목차
ABSTRACT
Ⅰ. 서론
Ⅱ. 재료 및 방법
Ⅲ. 결과
Ⅳ. 고찰 및 결론
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