지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2004.6
- 수록면
- 78 - 86 (9page)
이용수
초록· 키워드
오류제보하기
Panax ginseng occupies an important role in the folk medicine of China, Korea and Japan. The present study was undertaken to determine the radioprotective efficacy of ginseng root extract in the liver of Swiss albino mice. The animals were divided into 4 groups. Group I Only vehicle was administered. Group II-The animals received 10 mg/kg body weight ginseng root extract i.p. for 4 consecutive days. Group III-Animals were irradiated with 8Gy gamma radiation at the dose rate of 1.69 Gy/min at the distance of 80 cms. Group IV -Animals were given by ginseng root extract (10 mglkg body weight) continuously for 4 days and on 4th day they were irradiated with 8 Gy gamma radiation after 3D min. The animals from above groups were autopsied on I. 3, 7. 14 and 30 days. Biochemical estimations of phosphatases (acid & alkaline), LDH (lactate dehydrogenase), LPO (lipid peroxidation) and GSH (reduced glutathione) in liver and SGOT (serum glutamate oxaloacetate transaminase). SGPf (serum glutamate pyruvate transaminase) and alkaline phosphatase in serum were done. In ginseng treated group acid phosphatase (ACP), alkaline phosphatase (ALP). LPO and LDH in liver and SGOT, SGPf and alkaline phosphatase in serum did not show any significant alteration. However, a signiticant increase in GSH content in liver was recorded. In irradiated group there was a signiticant increase in ACP, ALP and LPO content in liver and SGOT & SGPT in serum was noted. Whereas, a significant decrease was recorded in GSH and LDH activity in liver and alkaline phosphatase activity in sel1lm. Pretreatment of ginseng with radiation significantly alters the biochemical parameters in liver and serum. A significant decline in ACP, ALP activity and LPO content in liver and SGOT and SGPf activity in serum was observed. However, a significant increase in GSH content and LDH activity in liver and ALP activity in serum was estimated. The present study suggests that pretreatment of ginseng before irradiation significantly protects the liver and maintains the enzyme activity.
목차
Abstract
INTRODUCTION
MATERIALS AND METHODS
RESULTS AND DISCUSSION
ACKNOWLEDGMENT
REFERENCES
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
The Anti-hepatotoxic Effect of Ginseng in Rats: Meta-analysis
Journal of Ginseng Research
2008 .06
-
Liver
대한외과학회 학술대회 초록집
2016 .11
-
인삼이 장기의 Alkaline Phosphatase활성과 혈중 무기 인량에 미치는 영향
대한생리학회지
1973 .01
-
Management of Radiation Injuries by Panax ginseng Extract
Journal of Ginseng Research
2011 .09
-
1개월 이상 한약을 복용한 101명의 간기능 검사에 대한 후향적 관찰
대한한의학회지
2010 .03
-
인삼(人蔘)이 흰 생쥐의 운동능력(運動能力) 및 유산생성량(乳酸生成量)에 미치는 영향(影響)
대한생리학회지
1975 .01
-
실험적 간장해에 대한 강활의 보호효과
Environmental Analysis Health and Toxicology
2005 .06
-
고지방식으로 생육한 생쥐 간에서 백삼과 홍삼 추출물의 항산화 효과
Journal of Ginseng Research
2005 .09
-
호르텐스극구흡충에서 Alkaline Phosphatase 및 Acid Phosphatase의 특성
대한의생명과학회지
1999 .06
-
수삼, 백삼 및 홍삼의 효과에 대한 비교 연구 흰쥐의 혈청내 몇가지 성분 함량 및 과산화지질생성에 미치는 영향
약학회지
1981 .01
-
인삼성분이 생쥐 간의 수종 효소활성에 미치는 영향 ( The effect of Ginseng Extracts on the Enzyme Activity in the Liver of Swiss Mice )
Journal of Ginseng Research
1980 .06
-
Effect of Korean Red Ginseng in chronic liver disease
Journal of Ginseng Research
2017 .10
-
The world ginseng market and the ginseng (Korea)
Journal of Ginseng Research
2013 .01
-
Effect of Cyclohexanone Treatment on the Serum Levels of Glutathione S-Transferase Activities in Acute Liver Damaged Rats
대한의생명과학회지
2001 .12
-
Study on Animal Liver Excretion Function Affected by Administration of Korean Ginseng Glycoside
약학회지
1976 .01
-
감마선 조사전 홍삼 추출물의 투여가 생쥐 간에서의 Superoxide dismutase의 활성과 지질 과산화에 미치는 영향
대한방사선치료학회지
1992 .01
-
An Association between Liver Markers and Physiological Variables : Comparison between Normal and Fatty Liver Subjects
대한의생명과학회지
2011 .06
이 논문의 저자 정보
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-ECN-0101-2009-524-014099594