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자료유형
학술저널
저자정보
저널정보
한국식품영양과학회 Journal of Food Science and Nutrition Journal of Food Science and Nutrition Vol.2 No.2
발행연도
1997.6
수록면
167 - 173 (7page)

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The inhibitory effects of kale juice on the growth and DNA incorporation of human cancer cells, using HT-29 colon cancer cells, MG-63 osteosarcoma cells, AGS gastric adenocarcinoma cells and K-562 leukemia cells, were studied. The growth of human cancer cells were inhibited in the presence of kale juice(10, 20 and 40μl/ml) and the effects were the juice concentration- and incubation time-dependent up to 6 days. When 20μl/ml of kale juice was added to the media of HT-29, MG-63, AGS and K-562 cancer cells, the cell growth after 6 or 4 days of incubation was retarded by 83~95% of control group. Morphological changes of HT-29 colon cancer cells were studied under inverted microscope. As the concentration of kale juice increased up to 20μl/ml, degree of cell aggregation was decreased. Moreover, the DNA incorporation of AGS gastric adenocarcinoma cells and MG-63 osteosarcoma cells which were labeled with [³H] thymidine was significantly reduced after 2 days of incubation at 37℃ with kale juice. Therefore, we concluded that kale juice strongly decreased the growth of various human cancer cells.

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Abstract

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MATERIALS AND METHODS

RESULTS AND DISCUSSION

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