지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국식품영양과학회 Journal of Food Science and Nutrition Journal of Food Science and Nutrition Vol.3 No.3
- 발행연도
- 1998.9
- 수록면
- 277 - 281 (5page)
이용수
초록· 키워드
오류제보하기
There is extensive evidence suggesting the protective role of fruits and vegetables against chemically induced carcinogenesis. We have tested the ability of a representative range of Korean vegetables to act as blocking agents against neoplastic initiation by determining the induction level of quinone reductase, an anticarcinogenic marker enzyme, in hepa1c1c7 cells exposed to vegetable extracts. Among thirty vegetables tested, Arctium lappa (Burdock), Brassica juncea (Mustard leaf), Pteridium aguilinum (Bracken) and Chrysanthemum coronarium (Crown daisy) caused a significant induction of quinone reductase activity with a limited increase in arylhydrocarbon hydroxylase activity. Combination of crown daisy with burdock had synergistic effect on quinone reductase induction. Quinone reductase-inducing activity was found mostly in hexane and ethylacetate fractions of MeOH extract of crown daisy while it was not detected in n-butanol and water fractions. Animal study using SD rats demonstrated that crown daisy intake induced quinone reductase activity in liver, kidney, lung, and small intestine, confirming the presence of potent QR inducer(s) in crown daisy. These data suggest that some vegetables including crown daisy induced QR merits further investigation as a potential cancer preventive agent in human.
목차
Abstract
INTRODUCTION
MATERIALS AND METHODS
RESULTS AND DISCUSSION
ACKNOWLEDGEMENTS
REFERENCES
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