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논문 기본 정보

자료유형
학술저널
저자정보
저널정보
한국식품영양과학회 Journal of Food Science and Nutrition Journal of Food Science and Nutrition Vol.4 No.1
발행연도
1999.3
수록면
43 - 46 (4page)

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Taurine is known to suppress oxidant-induced tissue injury by stabilizing biomembrane and scavanging free radicals. The purpose of this study was to determine the antioxidative and antimutagenic activities of taurine, and to compare those activities with major antioxidants. For the measurement of antioxidative capacity, 0.05, 0.1, 0.5 and 1.0 ㎎/ml of taurine, L-ascorbic acid, alpha-tocopherol, and BHT (dibutyl hydroxy toluene) were prepared and tested for their ability to donate electrons to DPPH (1,1-diphenyl-2-picryl-hydrazyl). Antimutagenic activity was examined using the Ames salmonella test system at concentrations of 600, 900, and 1200 ㎍/ml. Results indicated that taurine possesses electron-donating capacity, however, the degree of donation was very weak compared to the major antioxidants tested. However, taurine was evaluated as a potent mutation suppressor. Antimutagenic capacity was in increasing order BHT>taurine>L-ascorbic acid>alpha-tocopherol at concentrations of 600 and 900 ㎍/ml. There was a dose-dependent increase in antimutagenicity of these compounds, however, antimutagenicity of the 900 ㎍ taurine/plate was not significantly different from that of 1200 ㎍ taurine/plate. These results indicate that taurine effectively suppresses the mutagenicity of AFB₁ without noticeable electron donating ability.

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Abstract

INTRODUCTION

MATERIALS AND METHODS

RESULTS AND DISCUSSION

ACKNOWLEDGEMENTS

REFERENCES

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