지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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Alloimmunization to red blood cell (RBC) antigens may cause a delayed hemolytic transfusion reactions (DHTR) and a delayed serologic transfusion reactions (DSTR). In the present study, the frequency of alloimmunization and its clinical significance were evaluated. Also, transfusions were correlated with antibody formation. Alloimmunization rate was 0.63%. Alloimmunization rate in multiple transfused patients was 24.5%. The most common clinically significant alloantibodies of alloimmunized patients were found to be Rh antibodies (52.6%). Nine patients out of 38 (23.7%) became undetectable after the first detection. To be positive at antibody screening test after RBC transfusion was mean transfused numbers : 3.7 units, mean transfused periods : 56 days, mean transfused frequencies : 1.7 times. The results from antibody specificity and RBC transfusions were comparatively analyzed and it shows that Rh system antibodies were longer than other antibodies (P＜0.05). In case of disease group, malignant diseases was longer than other diseases (P＜0.05). In order to prevent the formation of RBC alloimmunization, irregular antibody screening tests were performed at propriety intervals in multiple transfused patients.
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재료 및 방법
결과
고찰
REFERENCES
참고문헌 (30)
참고문헌 신청
[단행본] - ME,Brecher / 2002 / Technical Manual / American Association of Blood Bank. Bethesda. MD, USA. : 410 ~
[학술지(정기간행물)] - SM,Coles / 1981 / Alloimmunization in two multitransfused patient populations / Transfusion 21 : 462 ~ 466
[학술지(정기간행물)] - W,Dameshek / 1998 / Isoimmunization with Rh factor in acquired hemolytic anemia / N Engl J Med 228 : 641 ~ 644
[단행본] - FDA Code of federations / / 2001(revised annually) / Government printing office.FDA Code of federations
[학술지(정기간행물)] - AM,Floss / 1986 / Multiple transfusions fail to provoke antibodies against blood cell antigens in human infacts / Transfusion 26 : 419 ~ 422
[학술지(정기간행물)] - SM,Coles / 1981 / Alloimmunization in two multitransfused patient populations / Transfusion 21 : 462 ~ 466
[학술지(정기간행물)] - W,Dameshek / 1998 / Isoimmunization with Rh factor in acquired hemolytic anemia / N Engl J Med 228 : 641 ~ 644
[단행본] - FDA Code of federations / / 2001(revised annually) / Government printing office.FDA Code of federations
[학술지(정기간행물)] - AM,Floss / 1986 / Multiple transfusions fail to provoke antibodies against blood cell antigens in human infacts / Transfusion 26 : 419 ~ 422
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UCI(KEPA) : I410-ECN-0101-2009-510-017357040