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논문 기본 정보

자료유형
학술저널
저자정보
유경희 (울산과학대학) 윤진숙 (계명대학교) 함유식 (울산시 남구 보건소)
저널정보
한국영양학회 한국영양학회지 한국영양학회지 제32권 제8호
발행연도
1999.12
수록면
887 - 896 (10page)

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The purpose of this research is to assess hematological and biochemical status and the prevalence of iron deficiency of pregnant women by gestational age to provide the primary data about iron nutritional status of pregnant women. Pregnant women visiting public health centers in Ulsan participated in study and were divided into 3 trimester by last menstrual period(LMP). Hemoglobin(Hgb), hematocrit(Hct) and mean corpuscular volume(MCV) among iron status indices were not statistically different from normal distribution, however total iron binding capacity(TIBC) and serum ferritin were skewed to left and serum iron and transferrin saturation(TS) were skewed to right. Hgb was positiveIy correlated with Hct( r = 0.93, p < 0.001) but TIBC was negatively corrclated with all indices. Serum ferritin was also correlated with all indices, especially with TS(r = 0.54, P < 0.001) . Red blood cell(RBC), Hgb, Hct and serum ferritin decreased in 2nd trimester significantly and increased in 3rd trimester but not reached to 1st trimester level. Mean corpuscular hemoglobin(MCH), mean corpuscular hemoglobin concentration(MCHC), Red cell distribution width(RDW), serum iron and TS were not significantly different by trimester, however when serum iron was adjusted with hematocrit to correct the hemodilution, it significantly decreased in 2nd trimester. MCV inereased in 2nd trimester and was maintained until late pregnancy, TIBC continued to increase throughout the trimester. The prevalence of anemia by CDC( Centers for Disease Control) Hgb criteria(Hgb < 11.0g/dl in 1st and 3rd trimester, Hgb < 10.5g/dl in 2nd trimester) was 2.8% in 1st trimester, 22.5% in 2nd trimester, 27.1% in 3rd trimester and was similar with prevalence by CDC Hct criteria(Hct < 33% in 1st and 3rd, Hct < 32% in 2nd). The prevalence of anemia of total subjects was 32.7% by WHO criteria(Hgb < 11.0g/ dl). Although almost iron status indices increased in 3rd trimester， the prevalence of anemia by different criteria of all indices increased throughout the trimester, so iron nutritional status was considered as serious during late pregnancy. However, since factors other than iron deficiency, such as infection， inflammation, other nutrient deficiency may also play a significant role, to differentiate the anemia due to mainly iron deficiency from the anemia due to other factors, serum ferritin is among the more useful indices in distinguishing the two conditions because it is depressed only in iron deficiency. Hgb<11.0g/dl and serum ferritin <12.0 ㎍/L as the criteria of iron deficiency anemia was suggested by CDC, 17.8% of all subjects were classified as iron deficient anemia, 14.9% as anemia from other reasons, 21.2% as iron deficiency and only 46.2% were in normal iron status. (Korean J Nutrition 32(8): 887~896, 1999)
#hematological analysis #pregnancy #anemia #iron status indices

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UCI(KEPA) : I410-ECN-0101-2012-594-004459316