지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2006.11
- 수록면
- 295 - 300 (6page)
이용수
초록· 키워드
오류제보하기
Iron bound to heme appears to be more bioavailable than iron salts. A clinical study was performed to investigate the absorption efficiency of heme-iron and iron-salt products available. Heme-iron and nonheme-iron supplements have become available in Korea. We performed iron absorption studies to compare the absorption of heme-iron polypeptide (HIP) products made from digested hemoglobin, produced in Korea (HIPk) and imported from Japan (HIj), with that of iron salts. In the study, 80 subjects were divided into 5 groups (n=56): placebo group; 12 ㎎ glucose, HIPk group; 12 ㎎ iron as HIPk, HIj group; 12 ㎎ iron as HIj, iron-salt group 1; 12 ㎎ of iron as ferrous aminoacetate, and iron-salt group 2; 100 ㎎ iron as ferrous aminoacetate. Changes in serum iron levels were measured at 3 and 5 hours post ingestion. Absorption of iron in HIPk was higher compared to HIj, iron-salt or placebo. There was a significant inverse correlation between low serum iron levels (＜80 ㎍/㎗) and iron absorption from HIPk. These results demonstrated that HIPk was more bioavailable, even taken with a meal, and would have potential advantages over iron salt or Hlj as an iron supplement Our results indicate that heme-iron absorption is regulated by iron status through a heme receptor, whereas iron-salt absorption is unregulated.
목차
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
Acknowledgments
Literature Cited
참고문헌 (30)
참고문헌 신청
[학술지(정기간행물)] - / 1991 / Inorganic biochemistry of iron metabolism : 29 ~ 58
[학술지(정기간행물)] - / 1992 / Contributions of heme and non-heme iron to human nutrition 31 : 333 ~ 367
[학술지(정기간행물)] - / 1993 / Regulation of iron absorption proteins involved in duodenal mucosal uptake and transport : 720 ~ 728
[학술지(정기간행물)] - / 1974 / Food iron absorption in man Applications of the two-pool extrinsic tag method to measure heme and nonheme iron absorption from the whole diet : 247 ~ 255
[학술지(정기간행물)] - / 2001 / An iron regulated ferrous reductase associated with the absorption of dietary iron 291 : 1755 ~ 1759
[학술지(정기간행물)] - / 1992 / Contributions of heme and non-heme iron to human nutrition 31 : 333 ~ 367
[학술지(정기간행물)] - / 1993 / Regulation of iron absorption proteins involved in duodenal mucosal uptake and transport : 720 ~ 728
[학술지(정기간행물)] - / 1974 / Food iron absorption in man Applications of the two-pool extrinsic tag method to measure heme and nonheme iron absorption from the whole diet : 247 ~ 255
[학술지(정기간행물)] - / 2001 / An iron regulated ferrous reductase associated with the absorption of dietary iron 291 : 1755 ~ 1759
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UCI(KEPA) : I410-ECN-0101-2012-594-004194336