지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2010.12
- 수록면
- 442 - 446 (5page)
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초록· 키워드
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Purpose: Papillary thyroid carcinomas (PTCs) often occur as multifocal tumors. The aim of this study was to investigate the clinical features and treatment of multifocal PTC.
Methods: A retrospective survey was carried out on 315 patients with PTC who underwent total thyroidectomy and central compartment neck dissection with or without lateral neck dissection from January 2007 to April 2010. The risk factors, including sex of patients, age at diagnosis, largest tumor size, extra-thyroidal extension, presence of thyroiditis, lymph node involvement, thyroid stimulating hormone and post operative follow-up results were analyzed between solitary and multifocal PTC group.
Results: Of those factors, the presence of central compartment and lateral neck lymph node and mean numbers of involvement lymph node were significantly related factors for the multifocality of the PTC.
Conclusion: Multifocus is one of the clinical features of PTC. And multifocal PTCs are associated with increased risk of central and lateral neck lymph node involvement, Therefore, total thyroidectomy and central compartment neck dissection could be the standard treatments. And lateral neck node dissection should be recommended for cases with clinically positive lateral neck lymph nodes.
Methods: A retrospective survey was carried out on 315 patients with PTC who underwent total thyroidectomy and central compartment neck dissection with or without lateral neck dissection from January 2007 to April 2010. The risk factors, including sex of patients, age at diagnosis, largest tumor size, extra-thyroidal extension, presence of thyroiditis, lymph node involvement, thyroid stimulating hormone and post operative follow-up results were analyzed between solitary and multifocal PTC group.
Results: Of those factors, the presence of central compartment and lateral neck lymph node and mean numbers of involvement lymph node were significantly related factors for the multifocality of the PTC.
Conclusion: Multifocus is one of the clinical features of PTC. And multifocal PTCs are associated with increased risk of central and lateral neck lymph node involvement, Therefore, total thyroidectomy and central compartment neck dissection could be the standard treatments. And lateral neck node dissection should be recommended for cases with clinically positive lateral neck lymph nodes.
목차
서론
방법
결과
고찰
결론
REFERENCES
참고문헌 (20)
참고문헌 신청
1. [학술지(정기간행물)] - Carcangiu ML / 1985 / Papillary carcinoma of the thyroid. A clinicopathologic study of 241 cases treated at the University of Florence, Italy / Cancer 55 : 805 ~ 828
2. [학술지(정기간행물)] - Iida F / 1969 / Study of intraglandular dissemination of thyroid cancer / Cancer 24 : 764 ~ 771
3. [학술지(정기간행물)] - Katoh R / 1992 / Multiple thyroid involvement (intraglandular metastasis) in papillary thyroid carcinoma. A clinicopathologic study of 105 consecutive patients / Cancer 70 : 1585 ~ 1590
4. [학술지(정기간행물)] - Park SY / 2006 / Analysis of differential BRAF(V600E) mutational status in multifocal papillary thyroid carcinoma: evidence of independent clonal origin in distinct tumor foci / Cancer 107 : 1831 ~ 1838
5. [학술지(정기간행물)] - Shattuck TM / 2005 / Independent clonal origins of distinct tumor foci in multifocal papillary thyroid carcinoma / N Engl J Med 352 : 2406 ~ 2412
2. [학술지(정기간행물)] - Iida F / 1969 / Study of intraglandular dissemination of thyroid cancer / Cancer 24 : 764 ~ 771
3. [학술지(정기간행물)] - Katoh R / 1992 / Multiple thyroid involvement (intraglandular metastasis) in papillary thyroid carcinoma. A clinicopathologic study of 105 consecutive patients / Cancer 70 : 1585 ~ 1590
4. [학술지(정기간행물)] - Park SY / 2006 / Analysis of differential BRAF(V600E) mutational status in multifocal papillary thyroid carcinoma: evidence of independent clonal origin in distinct tumor foci / Cancer 107 : 1831 ~ 1838
5. [학술지(정기간행물)] - Shattuck TM / 2005 / Independent clonal origins of distinct tumor foci in multifocal papillary thyroid carcinoma / N Engl J Med 352 : 2406 ~ 2412
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