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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2008.3
- 수록면
- 182 - 186 (5page)
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Purpose: Postoperative hypocalcemia is a common complication of thyroidectomy. This study evaluated the incidence and risk factors for postoperative hypocalcemia after total thyroidectomy.
Methods: There were 196 consecutive patients undergoing total thyroidectomy for thyroid cancer between September 2004 and February 2005 who were enrolled in this study. Patients were divided into two groups, those remaining normocalcemic (Group Ⅰ) and those who had hypocalcemia requiring treatment (Group Ⅱ). Group Ⅱ was subdivided into a transient hypocalcemic group (Group ⅡA) and a permanent hypocalcemic group (Group ⅡB). All groups were compared with regard to age, gender, histology, coexisting disease, T stage, bilateral lesions, primary total thyroidectomy versus secondary completion thyroidectomy, extent of lymph node dissection, and autotransplantation of the parathyroid gland.
Results: Among all patients, 139 (71%) were in Group I, 54 (27.5%) in Group ⅡA and 3 (1.5%) in Group ⅡB. On the multivariate analysis for risk factors compared between Group Ⅰ and Group Ⅱ, the T4 stage was the most significant for the development of postoperative hypocalcemia. On the univariate analysis comparing factors between Group ⅡA and Group ⅡB, the T4 stage and a complete thyroidectomy were significantly related to the development of permanent hypocalcemia.
Conclusion: The results of this study showed that the incidence of transient hypocalcemia, after total thyroidectomy, was 27.5%, while permanent hypocalcemia was detected in 1.5% of cases. The parathyroid glands should be preserved more carefully to avoid postoperative hypocalcemia in patients with high risk factors including T4 tumors and complete thyroidectomy procedures.
Methods: There were 196 consecutive patients undergoing total thyroidectomy for thyroid cancer between September 2004 and February 2005 who were enrolled in this study. Patients were divided into two groups, those remaining normocalcemic (Group Ⅰ) and those who had hypocalcemia requiring treatment (Group Ⅱ). Group Ⅱ was subdivided into a transient hypocalcemic group (Group ⅡA) and a permanent hypocalcemic group (Group ⅡB). All groups were compared with regard to age, gender, histology, coexisting disease, T stage, bilateral lesions, primary total thyroidectomy versus secondary completion thyroidectomy, extent of lymph node dissection, and autotransplantation of the parathyroid gland.
Results: Among all patients, 139 (71%) were in Group I, 54 (27.5%) in Group ⅡA and 3 (1.5%) in Group ⅡB. On the multivariate analysis for risk factors compared between Group Ⅰ and Group Ⅱ, the T4 stage was the most significant for the development of postoperative hypocalcemia. On the univariate analysis comparing factors between Group ⅡA and Group ⅡB, the T4 stage and a complete thyroidectomy were significantly related to the development of permanent hypocalcemia.
Conclusion: The results of this study showed that the incidence of transient hypocalcemia, after total thyroidectomy, was 27.5%, while permanent hypocalcemia was detected in 1.5% of cases. The parathyroid glands should be preserved more carefully to avoid postoperative hypocalcemia in patients with high risk factors including T4 tumors and complete thyroidectomy procedures.
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UCI(KEPA) : I410-ECN-0101-2013-514-002693454