지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2007.10
- 수록면
- 285 - 289 (5page)
이용수
초록· 키워드
오류제보하기
Purpose: Sentinel lymph node (SLN) dissection is now a widely used and accepted method for staging the axilla in breast cancer patients. The aim of this study was to determine the rate of axillary lymphatic recurrence and metastasis in breast cancer patients who had a negative SLNB.
Methods: A retrospective chart review from August of 2001 to December of 2003 was performed for all patients (n=89) who underwent a SLN biopsy and they had a negative SLN on the intraoperative frozen sections. Any additional axillary lymph node dissection was not performed even when the sentinel lymph node(s) were found to be positive by the permanent pathology. The patients received appropriate adjuvant therapy according to the characteristics of the primary tumor. All the patients who had breast conserving surgery received postoperative radiotherapy to the remaining breast, but not to the axilla.
Results: A mean of 4.92 LNs were removed per patient. Among the 89 patients whose sentinel lymph nodes were tumor-free on frozen section, 9 patients had metastatic lymph nodes on the permanent pathology. All the metastases were micrometastasis. Over a mean follow-up period of 53 months, one patient died of liver metastasis and one patient developed n ipsilateral breast recurrence. Only one patient developed an axillary recurrence.
Conclusion: SLNB provides accurate staging of breast cancer and this might be a good alternative to routine axillary lymph node dissection with incurring less surgical morbidity.
Methods: A retrospective chart review from August of 2001 to December of 2003 was performed for all patients (n=89) who underwent a SLN biopsy and they had a negative SLN on the intraoperative frozen sections. Any additional axillary lymph node dissection was not performed even when the sentinel lymph node(s) were found to be positive by the permanent pathology. The patients received appropriate adjuvant therapy according to the characteristics of the primary tumor. All the patients who had breast conserving surgery received postoperative radiotherapy to the remaining breast, but not to the axilla.
Results: A mean of 4.92 LNs were removed per patient. Among the 89 patients whose sentinel lymph nodes were tumor-free on frozen section, 9 patients had metastatic lymph nodes on the permanent pathology. All the metastases were micrometastasis. Over a mean follow-up period of 53 months, one patient died of liver metastasis and one patient developed n ipsilateral breast recurrence. Only one patient developed an axillary recurrence.
Conclusion: SLNB provides accurate staging of breast cancer and this might be a good alternative to routine axillary lymph node dissection with incurring less surgical morbidity.
목차
서론
방법
결과
고찰
결론
REFERENCES
참고문헌 (15)
참고문헌 신청
1. [학술지(정기간행물)] - Krag DN / 1998 / Minimal access surgery for staging regional lymph node: the sentinel nodes concept / Curr Probl Surg 35 : 951 ~ 1016
2. [학술지(정기간행물)] - Langer I / 2007 / Morbidity of sentinel lymph node biopsy (SLN) alone versus SLN and completion axillary lymph node dissection after breast cancer surgery: a prospective Swiss multicenter study on 659 patients / Ann Surg 245 : 452 ~ 461
3. [학술지(정기간행물)] - Mansel RE / 2006 / Randomized multicenter trial of sentinel node biopsy versus standard axillary treatment in operable breast cancer: the ALMANAC Trial / J Natl Cancer Inst 98 : 599 ~ 609
4. [학술지(정기간행물)] - Yoon SH / 2001 / Combined peritumoral and subareolar injection of blue dye improves sentinel lymph node localization rates / J Korean Surg Soc 60 : 148 ~ 153
5. [학술지(정기간행물)] - Fournier K / 2004 / Micrometastasis in the sentinel lymph node of breast cancer dose not mandate completion axillary dissection / Ann Surg 239 : 859 ~ 863
2. [학술지(정기간행물)] - Langer I / 2007 / Morbidity of sentinel lymph node biopsy (SLN) alone versus SLN and completion axillary lymph node dissection after breast cancer surgery: a prospective Swiss multicenter study on 659 patients / Ann Surg 245 : 452 ~ 461
3. [학술지(정기간행물)] - Mansel RE / 2006 / Randomized multicenter trial of sentinel node biopsy versus standard axillary treatment in operable breast cancer: the ALMANAC Trial / J Natl Cancer Inst 98 : 599 ~ 609
4. [학술지(정기간행물)] - Yoon SH / 2001 / Combined peritumoral and subareolar injection of blue dye improves sentinel lymph node localization rates / J Korean Surg Soc 60 : 148 ~ 153
5. [학술지(정기간행물)] - Fournier K / 2004 / Micrometastasis in the sentinel lymph node of breast cancer dose not mandate completion axillary dissection / Ann Surg 239 : 859 ~ 863
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UCI(KEPA) : I410-ECN-0101-2013-514-002670942