진행성 위암으로 진단된 위의 충돌종양(선암과 신경내분비암)

박병수; 조태용; 서형일; 김현성; 김대환; 전태용; 김동헌; 심문섭; 김지연

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자료유형: 학술저널

저자정보: 박병수 (부산대학교) 조태용 (부산대학교) 서형일 (부산대학교) 김현성 (부산대학교) 김대환 (부산대학교) 전태용 (부산대학교) 김동헌 (부산대학교) 심문섭 (부산대학교) 김지연 (부산대학교)

저널정보: 대한외과학회 Annals of Surgical Treatment and Research 대한외과학회지 Vol.73 No.2

발행연도: 2007.8

수록면: 173 - 177 (5page)

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The collision tumors have been reported in various organs and represent the coexistence of two adjacent but histologically distinct tumors in an organ without any histological admixture. A gastric collision tumor is rare and most gastric collision tumors involve an adenocarcinoma colliding with a lymphoma. A 48-year-old man was referred to our hospital for an evaluation of dyspepsia and upper abdominal discomfort. Endoscopy demonstrated the presence of an ulcerative lesion in the gastric antrum. The biopsy specimens confirmed a pathological diagnosis of an adenocarcinoma. After a radical subtotal gastrectomy, a thorough Histopathological examination revealed a collision tumor: a well-differentiated adenocarcinoma in the superficial layer (mucosa, submucosa) and a poorly differentiated neuroendocrine carcinoma in the deeper layer (muscularis propria, serosa). The patient received combination chemotherapy with cisplatin and etoposide. Para-aortic lymph node enlargement was observed on the abdominal computed tomography scanning, 3 years after surgery. The patient underwent chemotherapy with TS-1, and the size of lymph nodes was reduced. The patient continues to do well after a follow up period of 5 years 3 months. We report this case of gastric collision tumor (adenocarcinoma and neuroendocrine carcinoma) with a brief review of the relevant literature.

#Collision tumor #Neuroendocrine carcinoma #Stomach #충돌종양 #신경내분비암 #위

참고문헌 (16)

참고문헌 신청

1. [학술지(정기간행물)] - Boo YJ / 2007 / Gastric neuroendocrine carcinoma: clinicopathologic review and immunohistochemical study of E-cadherin and Ki-67 as prognostic markers / J Surg Oncol 95 : 110 ~ 117

2. [학술지(정기간행물)] - Liu SW / 2002 / Collision tumor of the stomach: a case report of mixed gastrointestinal stromal tumor and adenocarcinoma / J Clin Gastroenterol 35 : 332 ~ 334

3. [학술지(정기간행물)] - Yang GC / 1991 / Mixed (composite) glandular-endocrine cell carcinoma of the stomach. Report of a case and review of literature / Am J Surg Pathol 15 : 592 ~ 598

4. [학술지(정기간행물)] - Morishita Y / 2005 / Collision tumor of the stomach: a rare case of an adenocarcinoma and carcinoid tumor / Arch Pathol Lab Med 129 : 407 ~ 409

5. [학술지(정기간행물)] - Yamashina M / 1985 / Concurrent occurrence of adenocarcinoma and carcinoid tumor in the stomach: a composite tumor or collision tumors? / Am J Clin Pathol 83 : 233 ~ 236

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