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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2009.12
- 수록면
- 215 - 220 (6page)
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Purpose: There has been controversy concerning which is the best treatment method for small hepatocellular carcinoma between anatomical resection (AR) and non-anatomical resection (NAR). In this retrospective study, we investigated the outcomes of surgical resection for small hepatocellular carcinoma and the clinical results depending on the type of hepatectomy.
Methods: We performed an analysis of the clinicopathologic factors of forty eight patients who underwent hepatectomy for a small (＜2 cm) hepatocellular carcinoma between 1990 and 2005. The AR was defined as the resection based on the segment or lobe, as proposed by Couinaud. NAR was defined as the resection of a lesion without regard to the segmental or lobar anatomy, as proposed by Couinaud. The patients were divided into 2 groups base on the hepatectomy procedure: AR (n=24) and NAR (n=24).
Results: There were no significant difference between the two groups for the general characteristics of the patients and the clinicopathologic findings, except for ICG R15. The mean ICG R15 in the AR and NAR groups was 11.8±6.9 and 22.4±15.6, respectively, The NAR group had significantly higher ICG R15 values. The cumulative 1, 3 and 5 year overall survival rates in the AR and NAR groups were 95.8%, 68.2% and 61.3%, and 76.6%, 59.0% and 52.5%, respectively. The cumulative overall survival rate and the mean 5 year disease free survival rate in the AR group (69.8%) were higher than those of the NAR group (45.8%). However, there was no statistically significant difference.
Conclusion: Depending on the surgical results of this study, there was no statistically significant difference in the outcomes between the AR and NAR groups.
Methods: We performed an analysis of the clinicopathologic factors of forty eight patients who underwent hepatectomy for a small (＜2 cm) hepatocellular carcinoma between 1990 and 2005. The AR was defined as the resection based on the segment or lobe, as proposed by Couinaud. NAR was defined as the resection of a lesion without regard to the segmental or lobar anatomy, as proposed by Couinaud. The patients were divided into 2 groups base on the hepatectomy procedure: AR (n=24) and NAR (n=24).
Results: There were no significant difference between the two groups for the general characteristics of the patients and the clinicopathologic findings, except for ICG R15. The mean ICG R15 in the AR and NAR groups was 11.8±6.9 and 22.4±15.6, respectively, The NAR group had significantly higher ICG R15 values. The cumulative 1, 3 and 5 year overall survival rates in the AR and NAR groups were 95.8%, 68.2% and 61.3%, and 76.6%, 59.0% and 52.5%, respectively. The cumulative overall survival rate and the mean 5 year disease free survival rate in the AR group (69.8%) were higher than those of the NAR group (45.8%). However, there was no statistically significant difference.
Conclusion: Depending on the surgical results of this study, there was no statistically significant difference in the outcomes between the AR and NAR groups.
목차
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방법
결과
고찰
참고문헌
참고문헌 (28)
참고문헌 신청
1. [학술지(정기간행물)] - Macintosh EL / 1992 / Hepatic resection in patients with cirrhosis and hepatocellular carcinoma / Surg Gynecol Obstet 17 : 245 ~ 254
2. [학술지(정기간행물)] - Oka H / 1992 / Prospective study of detection of hepatocellular carcinoma in patients with cirrhosis / Hepatology 12 : 680 ~ 687
3. [학술지(정기간행물)] - Cottone M / 1994 / Screening for hepatocellular carcinoma in patients with child's a cirrhosis: an 8-year prospective study by ultrasound and alphafetoprotein / J Hepatol 21 : 1029 ~ 1034
4. [학술지(정기간행물)] - Ebara M / 1986 / Natural history of minute hepatocellular carcinoma smaller than three centimeters complicating cirrhosis. A study in 22 patients / Gastroenterol 90 : 289 ~ 298
5. [학술지(정기간행물)] - Barbara L / 1992 / Natural history of small untreated hepatocellular carcinoma in cirrhosis: a multivariate analysis of prognostic factors of tumor growth rate and patient survival / Hepatology 16 : 132 ~ 137
2. [학술지(정기간행물)] - Oka H / 1992 / Prospective study of detection of hepatocellular carcinoma in patients with cirrhosis / Hepatology 12 : 680 ~ 687
3. [학술지(정기간행물)] - Cottone M / 1994 / Screening for hepatocellular carcinoma in patients with child's a cirrhosis: an 8-year prospective study by ultrasound and alphafetoprotein / J Hepatol 21 : 1029 ~ 1034
4. [학술지(정기간행물)] - Ebara M / 1986 / Natural history of minute hepatocellular carcinoma smaller than three centimeters complicating cirrhosis. A study in 22 patients / Gastroenterol 90 : 289 ~ 298
5. [학술지(정기간행물)] - Barbara L / 1992 / Natural history of small untreated hepatocellular carcinoma in cirrhosis: a multivariate analysis of prognostic factors of tumor growth rate and patient survival / Hepatology 16 : 132 ~ 137
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