메뉴 건너뛰기
Library Notice
Institutional Access
If you certify, you can access the articles for free.
Check out your institutions.
ex)Hankuk University, Nuri Motors
Log in Register Help KOR
Subject

Quantitative Alpha Fetoprotein Detection with a Piezoelectric Microcantilever Mass Sensor
Recommendations
Search
Questions

압전 마이크로캔틸레버 질량센서를 이용한 정량적 알파태아단백 검출

논문 기본 정보

Type
Academic journal
Author
Sangkyu Lee (포항공과대학교) Jongyun Cho (포항공과대학교) Yeolho Lee (삼성종합기술연구원) Sangmin Jeon (포항공과대학교) Hyung Joon Cha (포항공과대학교) Wonkyu Moon (포항공과대학교)
Journal
The Korean Society For Nondestructive Testing JOURNAL OF THE KOREAN SOCIETY FOR NONDESTRUCTIVE TESTING Vol.31 No.5 KCI Accredited Journals
Published
2011.10
Pages
487 - 493 (7page)

Usage

cover
📌
Topic
📖
Background
🔬
Method
🏆
Result
Quantitative Alpha Fetoprotein Detection with a Piezoelectric Microcantilever Mass Sensor
Ask AI
Recommendations
Search
Questions

Abstract· Keywords

Report Errors
Alpha fetoprotein(AFP), which is serological marker for hepatocellular carcinoma, was quantitatively measured by its normal concentration, 10 ng/ml, with a label-free piezoelectric microcantilever mass sensor. The principle of detection is based on changes in the resonant frequency of the piezoelectric microcantilever before and after target molecules are attached to it, and its resonant frequency is measured electrically using a conductance spectrum. The resonant frequency of the developed sensor is approximately 1.34 ㎒ and the mass sensitivity is approximately 175 ㎐/pg. The sensor has high reliability as mass sensor by reducing the effect of surface stress on resonant frequency due to attached proteins. ‘Dip and dry’ technique was used to react the sensor with reagents for immobilizing AFP antibody on the sensor and detecting AFP antigen. The measured mass of the detected AFP antigen was 6.02 pg at the concentration of 10 ng/ml, and 10.67 pg at 50 ng/ml when the immunoreaction time was 10 min.

Contents

초록
Abstract
1. 서론
2. 압전 아미크로캔틸레버 질량센서
3. 실험
4. 실험 결과 및 고찰
5. 결론
참고문헌

References (12)

Add References

Related Authors

Frequently Viewed Together

Recently viewed articles

Comments(0)

0

Write first comments.

UCI(KEPA) : I410-ECN-0101-2014-500-003269790