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논문 기본 정보

자료유형
학술저널
저자정보
Sun Hee Kim (Health and Environment Institute of Gwangju) Mihee Seo (Health and Environment Institute of Gwangju) Jung Wook Park (Health and Environment Institute of Gwangju) Sun Ju Cho (Health and Environment Institute of Gwangju) Yi Deun Ha (Health and Environment Institute of Gwangju) Dong-Ryong Ha (Health and Environment Institute of Gwangju) Eun-Sun Kim (Health and Environment Institute of Gwangju) Hae Ji Kang (Korea Centers for Disease Control and Prevection) Sung Soon Kim (Korea Centers for Disease Control and Prevection) Kisoon Kim (Korea Centers for Disease Control and Prevection) Jae Keun Chung (Health and Environment Institute of Gwangju)
저널정보
대한미생물학회 JOURNAL OF BACTERIOLOGY AND VIROLOGY JOURNAL OF BACTERIOLOGY AND VIROLOGY Vol.45 No.2
발행연도
2015.6
수록면
132 - 137 (6page)

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초록· 키워드

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The recent mumps epidemic in South Korea has generated a large amount of public concern. This study has attempted to analyze molecular epidemiological changes of mumps virus circulating in Gwangju metropolitan area, South Korea. 953 throat swab samples were collected from patients with parotitis from May 2013 to July 2014. The majority (71.5%) of these cases have occurred in middle or high school students aged from 15 to 19 years. All samples were tested using a reverse transcription polymerase chain reaction (RT-PCR) that targets the short hydrophobic (SH) gene of the virus. Mumps virus SH gene was detected in 39.2% (374/953) of samples. And 82 RT-PCR products were randomly selected for nucleotide sequencing analysis. All of these sequences were determined as genotype I by phylogenetic analysis and showed the highest nucleic acid similarity (99%) with Dg1062/Korea/98 (GenBank accession no. AY309060). These results suggested that appearance of new genotype or genetic variation at the nucleotide level could be ruled out to evaluate main cause of recent mumps outbreak in Gwangju metropolitan area.

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INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
REFERENCES

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