지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
이용수
초록· 키워드
오류제보하기
To provide guidelines for the empirical treatment of urinary tract infections, we observed annual changes in the occurrence frequency and antimicrobial susceptibility of urinary isolates in a university hospital in the Chungbuk province, South Korea, over a period of 10 years (2004~2013). Escherichia coli (38.2%), Enterococcus faecalis (11.7%), Klebsiella pneumoniae (7.3%), Pseudomonas aeruginosa (4.3%), E. faecium (4.3%), and Staphylococcus aureus (4.1%) were commonly isolated urinary pathogens. The prevalence of E. coli, E. faecium and Streptococcus agalactiae were significantly higher in females (P < 0.001), whereas E. faecalis, P. aeruginosa and S. aureus were significantly more common in male patients (P < 0.001). E. coli mostly frequently showed resistance to ampicillin (67.94%), followed by trimethoprim/sulfamethoxazole (36.06%) and ciprofloxacin (26.84%). Over the studied time period, resistance rates of E. coli to ciprofloxacin significantly increased (20.44% to 33.55%). Moreover, extended-spectrum β-lactamase (ESBL) producing isolates also significantly increased in E. coli (4.2% to 18.3%) and K. pneumoniae (9.6% to 26.9%). In addition, the proportion of vancomycin-resistant Enterococcus facium (VRE) also increased (15.7% to 25.0%). In conclusion, over the last 10 years, the proportions of ciprofloxacin resistant E. coli and multidrug-resistant bacteria, such as ESBL and VRE have significantly increased. This trend must be strictly controlled and demonstrates the need for more updated guidelines for the treatment of urinary tract infections.
목차
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (34)
참고문헌 신청
[학술지(정기간행물)] - Boyce JM / 1994 / Outbreak of multidrug-resistant Enterococcus faecium with transferable vanB class vancomycin resistance / J Clin Microbiol 32 : 1148 ~ 1153
[학술지(정기간행물)] - Bush K / 2001 / New β-lactamases in gram-negative bacteria: diversity and impact on the selection of antimicrobial therapy / Clin Infec Dis 32 : 1085 ~ 1089
[학술지(정기간행물)] - Chazan B / 2004 / Improved antimicrobial susceptibility of community-acquired uropathogens in northern Israel (1995-1999-2002) / Int J Antimicrob Agents 24 : 89 ~ 92
[학술지(정기간행물)] - 정경태 / 2010 / Nationwide Surveillance Study of Vancomycin-Intermediate Staphylococcus aureus Strains in Korean Hospitals from 2001 to 2006 / Journal of Microbiology and Biotechnology 20 (3) : 637 ~ 642
[기타자료] - Clinical and Laboratory Standards Institute / 2012 / Performance standards for antimicrobial susceptibility testing: twenty two informational supplement (M100-S22) / CLSI
[학술지(정기간행물)] - Bush K / 2001 / New β-lactamases in gram-negative bacteria: diversity and impact on the selection of antimicrobial therapy / Clin Infec Dis 32 : 1085 ~ 1089
[학술지(정기간행물)] - Chazan B / 2004 / Improved antimicrobial susceptibility of community-acquired uropathogens in northern Israel (1995-1999-2002) / Int J Antimicrob Agents 24 : 89 ~ 92
[학술지(정기간행물)] - 정경태 / 2010 / Nationwide Surveillance Study of Vancomycin-Intermediate Staphylococcus aureus Strains in Korean Hospitals from 2001 to 2006 / Journal of Microbiology and Biotechnology 20 (3) : 637 ~ 642
[기타자료] - Clinical and Laboratory Standards Institute / 2012 / Performance standards for antimicrobial susceptibility testing: twenty two informational supplement (M100-S22) / CLSI
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UCI(KEPA) : I410-ECN-0101-2016-510-001658733