지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.6
- 수록면
- 165 - 170 (6page)
이용수
초록· 키워드
오류제보하기
Periodontitis is a disease that leads to destruction of the soft and hard tissues of periodontium, which can result in periodontal bone loss and tooth loss in severe cases. Atherosclerosis is a disease characterized by artery wall thickening as a result of invasion and accumulation of foam cells. Epidemiologic studies have suggested the association with periodontitis and atherosclerosis. Periodontopathogens are frequently found in atheroma plaque. The possible mechanisms for systemic dissemination of oral bacteria have been suggested: 1) direct translocation of bacteria from dental plaque to systemic circulation through transcellular mechanism or by physical perturbations of the gingiva, 2) indirect dissemination to distant sites via survival in immune cells including macrophages and dendritic cells. There are several mechanisms by which oral bacteria may contribute to atherosclerosis development: 1) activation of innate immune response, 2) mediators activated by oral bacteria and 3) involvement of cytokines and heat shock proteins from oral bacteria. Thus, better understanding the role of periodontitis in atherosclerosis may be the key to improve the prevention and treatment of atherosclerosis.
목차
INTRODUCTION
CONCLUSIONS
REFERENCES
참고문헌 (27)
참고문헌 신청
[학술지(정기간행물)] - Gomes MS / 2012 / Association between self-reported oral health, tooth loss and atherosclerotic burden / Braz Oral Res 26 : 436 ~ 442
[학술지(정기간행물)] - Hujoel PP / 2000 / Periodontal disease and coronary heart disease risk / JAMA 284 : 1406 ~ 1410
[학술지(정기간행물)] - Page RC / 1999 / Milestones in periodontal research and the remaining critical issues / J Periodontal Res 34 : 331 ~ 339
[학술지(정기간행물)] - Cortelli SC / 2013 / Frequency of periodontal pathogens in equivalent peri-implant and periodontal clinical statuses / Arch Oral Biol 58 : 67 ~ 74
[학술지(정기간행물)] - Mysak J / 2014 / Porphyromonas gingivalis: major periodontopathic pathogen overview / J Immunol Res 2014 : 476068 ~
[학술지(정기간행물)] - Hujoel PP / 2000 / Periodontal disease and coronary heart disease risk / JAMA 284 : 1406 ~ 1410
[학술지(정기간행물)] - Page RC / 1999 / Milestones in periodontal research and the remaining critical issues / J Periodontal Res 34 : 331 ~ 339
[학술지(정기간행물)] - Cortelli SC / 2013 / Frequency of periodontal pathogens in equivalent peri-implant and periodontal clinical statuses / Arch Oral Biol 58 : 67 ~ 74
[학술지(정기간행물)] - Mysak J / 2014 / Porphyromonas gingivalis: major periodontopathic pathogen overview / J Immunol Res 2014 : 476068 ~
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