지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한외과학회 Annals of Surgical Treatment and Research Annals of Surgical Treatment and Research Vol.89 No.1
- 발행연도
- 2015.6
- 수록면
- 43 - 47 (5page)
이용수
초록· 키워드
오류제보하기
Purpose: Empirical antibiotics in complicated intra-abdominal infection (c-IAI), such as secondary peritonitis are a first step of treatment. Empirical antibiotic regimen is very diverse. Ceftriaxone plus metronidazole regimen (CMR) is one of the empirical antibiotic regimens used in treatment of c-IAI. However, although CMR is a widely used empirical antibiotic regimen, study regarding success, failure or efficacy of CMR has been poorly understood. This retrospective study is conducted to compare the clinical efficacy of this regimen in c-IAI according to clinical characteristics.
Methods: The subjects were patients in this hospital who were diagnosed as secondary peritonitis between 2009 and 2013. Retrospective analysis was performed based on the records made after surgery regarding clinical characteristics including albumin level, blood pressure, pulse rate, respiration rate, smoking, age, sex, body mass index, hemoglobin, coexisting disease, leukocytosis, and APACHE (acute physiology and chronic health evaluation) II score.
Results: A total of 114 patients were enrolled. In univariated analysis, the success and failure of CMR showed significant association with preoperative low albumin, old age, and preoperative tachycardia. In multivariated analysis, low albumin and preoperative tachycardia were significant.
Conclusion: It is thought that an additional antibiotic treatment plan is necessary in patients with low albumin and tachycardia when the empirical antibiotic regimen is CMR in c-IAI. Conduct of research through well-designed prospective randomized clinical study is also necessary in order to evaluate the appropriateness of CMR and decide on a proper empirical antibiotic regimen between many regimens in c-IAI based on our country.
Methods: The subjects were patients in this hospital who were diagnosed as secondary peritonitis between 2009 and 2013. Retrospective analysis was performed based on the records made after surgery regarding clinical characteristics including albumin level, blood pressure, pulse rate, respiration rate, smoking, age, sex, body mass index, hemoglobin, coexisting disease, leukocytosis, and APACHE (acute physiology and chronic health evaluation) II score.
Results: A total of 114 patients were enrolled. In univariated analysis, the success and failure of CMR showed significant association with preoperative low albumin, old age, and preoperative tachycardia. In multivariated analysis, low albumin and preoperative tachycardia were significant.
Conclusion: It is thought that an additional antibiotic treatment plan is necessary in patients with low albumin and tachycardia when the empirical antibiotic regimen is CMR in c-IAI. Conduct of research through well-designed prospective randomized clinical study is also necessary in order to evaluate the appropriateness of CMR and decide on a proper empirical antibiotic regimen between many regimens in c-IAI based on our country.
목차
INTRODUCTION
METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (19)
참고문헌 신청
[학술지(정기간행물)] - Solomkin JS. / 2010 / Diagnosis and management of complicated intra-abdominal infection in adults and children : guidelines by the Surgical Infection Society and the Infectious Diseases Society of America / Surg Infect(Larchmt) 11 : 79 ~ 109
[학술지(정기간행물)] - Sartelli M. / 2013 / 2013 WSES guidelines for management of intraabdominal infections / World J Emerg Surg 8 : 3 ~
[학술지(정기간행물)] - Marshall JC. / 2003 / Intensive care unit management of intra-abdominal infection / Crit Care Med 31 : 2228 ~ 2237
[학술지(정기간행물)] - Menichetti F. / 2009 / Definition and classification of intra-abdominal infections / J Chemother 21 (Suppl 1) : 3 ~ 4
[학술지(정기간행물)] - Solomkin JS. / 2003 / Guidelines for the selection of anti-infective agents for complicated intraabdominal infections / Clin Infect Dis 37 : 997 ~ 1005
[학술지(정기간행물)] - Sartelli M. / 2013 / 2013 WSES guidelines for management of intraabdominal infections / World J Emerg Surg 8 : 3 ~
[학술지(정기간행물)] - Marshall JC. / 2003 / Intensive care unit management of intra-abdominal infection / Crit Care Med 31 : 2228 ~ 2237
[학술지(정기간행물)] - Menichetti F. / 2009 / Definition and classification of intra-abdominal infections / J Chemother 21 (Suppl 1) : 3 ~ 4
[학술지(정기간행물)] - Solomkin JS. / 2003 / Guidelines for the selection of anti-infective agents for complicated intraabdominal infections / Clin Infect Dis 37 : 997 ~ 1005
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