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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 충남대학교 농업과학연구소 Korean Journal of Agricultural Science Korean Journal of Agricultural Science Vol.43 No.5
- 발행연도
- 2016.12
- 수록면
- 742 - 749 (8page)
이용수
초록· 키워드
오류제보하기
Boar taint, an unpleasant odor of pork, is associated with two substances including androstenone and skatole. Testosterone is a steroid hormone as well as a strong predictor for androstenone secretion. Isoflavones of soy origin play a role in modulating the metabolism of sex hormones. Although several methods responsible for reducing boar taint are under investigation, the precise mechanism by which isoflavones reduce testosterone has not yet been identified. The objective of the current study was to investigate the effects of isoflavones extracted from a soy by-product on the concentration of serum testosterone in mouse. A total of 24 mice were supplemented with basal diet (control), daidzin plus genistin mix (T1), or isoflavone extracts (T2). After 11 days of treatment, size and weight of testis, as well as the concentration of sex hormones, including testosterone and estrogen, were analyzed. There was no difference in size or weight of testis from mice among control, T1, and T2. Serum testosterone levels were significantly decreased (p < 0.05) both in T1 and T2 when compared with the control group. Furthermore, estrogen concentration in blood was increased (p < 0.05) in T2 (numerically increased in T1) compared with the control group. Taken together, the use of isoflavones extracted from soy by-products would be a plausible strategy for reducing testosterone level, ultimately reducing boar taint without castration of piglets.
목차
Abstract
Introduction
Materials and Methods
Results and Discussion
Conclusion
References
참고문헌 (24)
참고문헌 신청
Akingbemi BT / 2007 / Exposure to phytoestrogens in the perinatal period affects androgen secretion by testicular Leydig cells in the adult rat / Endocrinology 148:4475~4488
Bateman HL / 2008 / Disrupted female reproductive physiology following neonatal exposure to phytoestrogens or estrogen specific ligands is associated with decreased GnRH activation and kisspeptin fiber density in the hypothalamus / Neurotoxicology 29:988~997
Cederroth CR / 2010 / Potential detrimental effects of a phytoestrogen-rich diet on male fertility in mice / Molecular and Cellular Endocrinology 321:152~160
Cimafranca MA / 2010 / Acute and chronic effects of oral genistein administration in neonatal mice / Biology of Reproduction 83:114~121
Cline JM / 2004 / Effects of dietary isoflavone aglycones on the reproductive tract of male and female mice / Toxicologic Pathology 32:91~99
Bateman HL / 2008 / Disrupted female reproductive physiology following neonatal exposure to phytoestrogens or estrogen specific ligands is associated with decreased GnRH activation and kisspeptin fiber density in the hypothalamus / Neurotoxicology 29:988~997
Cederroth CR / 2010 / Potential detrimental effects of a phytoestrogen-rich diet on male fertility in mice / Molecular and Cellular Endocrinology 321:152~160
Cimafranca MA / 2010 / Acute and chronic effects of oral genistein administration in neonatal mice / Biology of Reproduction 83:114~121
Cline JM / 2004 / Effects of dietary isoflavone aglycones on the reproductive tract of male and female mice / Toxicologic Pathology 32:91~99
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UCI(KEPA) : I410-ECN-0101-2017-520-002298955