지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한외과학회 Annals of Surgical Treatment and Research Annals of Surgical Treatment and Research Vol.92 No.4
- 발행연도
- 2017.4
- 수록면
- 200 - 207 (8page)
이용수
이 논문의 연구 히스토리 (3)
2016
Oncologic outcomes of stage IIIA rectal cancer : Comparison with IIA and IIB/C rectal cancer
Byoung Chul Lee
,
In Ja Pa
,
k
외 6명
대한외과학회 학술대회 초록집
2016.05
학술대회자료
Is pathologic regression level of metastatic lymph node after preoperative chemoradiotherapy for rectal cancer associated with oncologic outcomes?
Byoung Chul Lee
,
In Ja Pa
,
k
외 8명
대한외과학회 학술대회 초록집
2016.05
학술대회자료
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초록· 키워드
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Purpose: To investigate patterns of recurrence and oncologic outcomes after recurrence between preoperative and postoperative chemoradiotherapy (CRT).
Methods: Records of patients with stage II or III locally advanced rectal cancer seen between January 2000 and December 2010 were analyzed. The outcomes for patients undergoing preoperative CRT followed by radical resection (n = 466) were compared with outcomes of patients matched for sex, age, and stage who had surgery and then postoperative CRT (n = 466). Recurrence rates and sites, treatment of recurrence, and oncologic outcomes after recurrence were investigated. The rate of sphincter preservation and permanent stoma formation were also evaluated.
Results: Recurrence occurred in 124 and 140 patients in the pre- and postoperative CRT groups, respectively. The local and systemic recurrence rates were 3.6% and 20.8%, respectively, in the preoperative CRT group and 3.0% and 25.3%, respectively, in the postoperative CRT group (P = 0.245). Time to recurrence was longer in the postoperative CRT group (19 months vs. 24.2 months, P = 0.029). The overall rates of sphincter preservation (sphincter preservation operation and postoperative permanent stoma formation) did not significantly different between the two groups (P = 0.381). The 5-year overall survival rate after recurrence did not differ between the two groups (25.6% vs. 18.6%, P = 0.051).
Conclusion: Preoperative and postoperative CRT are both safe and suitable treatment methods for rectal cancer, so the choice can be tailored to the patient’s situation.
Methods: Records of patients with stage II or III locally advanced rectal cancer seen between January 2000 and December 2010 were analyzed. The outcomes for patients undergoing preoperative CRT followed by radical resection (n = 466) were compared with outcomes of patients matched for sex, age, and stage who had surgery and then postoperative CRT (n = 466). Recurrence rates and sites, treatment of recurrence, and oncologic outcomes after recurrence were investigated. The rate of sphincter preservation and permanent stoma formation were also evaluated.
Results: Recurrence occurred in 124 and 140 patients in the pre- and postoperative CRT groups, respectively. The local and systemic recurrence rates were 3.6% and 20.8%, respectively, in the preoperative CRT group and 3.0% and 25.3%, respectively, in the postoperative CRT group (P = 0.245). Time to recurrence was longer in the postoperative CRT group (19 months vs. 24.2 months, P = 0.029). The overall rates of sphincter preservation (sphincter preservation operation and postoperative permanent stoma formation) did not significantly different between the two groups (P = 0.381). The 5-year overall survival rate after recurrence did not differ between the two groups (25.6% vs. 18.6%, P = 0.051).
Conclusion: Preoperative and postoperative CRT are both safe and suitable treatment methods for rectal cancer, so the choice can be tailored to the patient’s situation.
목차
INTRODUCTION
METHODS
RESULTS
DISCUSSION
ACKNOWLEDGEMENTs
REFERENCES
참고문헌 (23)
참고문헌 신청
[학술지(정기간행물)] - Heald RJ / 1986 / Recurrence and survival after total mesorectal excision for rectal cancer / Lancet 1 : 1479 ~ 1482
[학술지(정기간행물)] - Obrand DI / 1997 / Incidence and patterns of recurrence following curative resection for colorectal carcinoma / Dis Colon Rectum 40 : 15 ~ 24
[학술지(정기간행물)] - Tjandra JJ / 2007 / Follow-up after curative resection of colorectal cancer : a metaanalysis / Dis Colon Rectum 50 : 1783 ~ 1799
[학술지(정기간행물)] - Sauer R / 2004 / Preoperative versus postoperative chemoradiotherapy for rectal cancer / N Engl J Med 351 : 1731 ~ 1740
[학술지(정기간행물)] - Kobayashi H / 2007 / Characteristics of recurrence and surveillance tools after curative resection for colorectal cancer : a multicenter study / Surgery 141 : 67 ~ 75
[학술지(정기간행물)] - Obrand DI / 1997 / Incidence and patterns of recurrence following curative resection for colorectal carcinoma / Dis Colon Rectum 40 : 15 ~ 24
[학술지(정기간행물)] - Tjandra JJ / 2007 / Follow-up after curative resection of colorectal cancer : a metaanalysis / Dis Colon Rectum 50 : 1783 ~ 1799
[학술지(정기간행물)] - Sauer R / 2004 / Preoperative versus postoperative chemoradiotherapy for rectal cancer / N Engl J Med 351 : 1731 ~ 1740
[학술지(정기간행물)] - Kobayashi H / 2007 / Characteristics of recurrence and surveillance tools after curative resection for colorectal cancer : a multicenter study / Surgery 141 : 67 ~ 75
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UCI(KEPA) : I410-ECN-0101-2017-514-002372381