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Molecular epidemiological study of norovirus gastroenteritis outbreaks in Gyeonggi-Do from 2014 to 2015
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2014-2015년 경기지역 노로바이러스성 식중독의 분자역학적 특성분석

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Type
Academic journal
Author
Soo-Jung Nam (경기도보건환경연구원) Po-Hyun Park (경기도보건환경연구원) Sun-Jae Bang (경기도보건환경연구원) Jeong-Weon Huh (경기도보건환경연구원) Hee-Jeong Yun (경기도보건환경연구원) Kwang-Hee Park (경기도보건환경연구원) Mi-Hye Yoon (경기도보건환경연구원)
Journal
The Microbiological Society of Korea Korean Journal of Microbiology Vol.54 No.1 KCI Accredited Journals SCOPUS
Published
2018.3
Pages
24 - 30 (7page)

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Molecular epidemiological study of norovirus gastroenteritis outbreaks in Gyeonggi-Do from 2014 to 2015
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Norovirus infection is a leading cause of nonbacterial gastroenteritis outbreaks. New variants of GII.4 have emerged approximately every 2~3 years and have caused norovirus gastroenteritis pandemics globally. In this study, analysis and molecular genetic characteristics of the norovirus gastroenteritis outbreaks 2,917 samples in Gyeonggi-Do from 2014 to 2015. As a result, 247 samples out of 2,917 samples are positive for norovirus. Norovirus molecular genetic characteristics of the GI 8 types (GI-1, 2, 3, 4, 5, 6, 12, 14), GII 10 types (GII - 2, 3, 4, 5, 6, 11, 12, 14, 16, 17). Genome sequences of isolated noroviruses were similar to those of new GII.17 Kawasaki 2014 variants with 96.6 identity, suggesting that these viruses were imported from overseas. 44% of virus incidence was originated from school meal service. Therefore, a continuous monitoring and school sanitation should be required for preventing a massive virus outbreak.
#genotype #norovirus #outbreak #variant

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References (15)

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Bartsch, S.M., Lopman, B.A., Ozawa, S., Hall, A.J., and Lee, B.Y. 2016. Global economic burden of norovirus gastroenteritis. PLoS One 11, e0151219. de Graaf, M., van Beek, J., Vennema, H., Podkolzin, A.T., Hewitt, J., Bucardo, F., Templeton, K., Mans, J., Nordgren, J., Reuter, G., et al. 2015. Emergence of a novel GII.17 norovirus-End of the GII.4 era? Euro Surveil. 20, 1?8. Gao, Z., Liu, B., Huo, D., Yan, H., Jia, L., Du, Y., Qian, H., Yang, Y., Wang, X., Li, J., et al. 2015. Increased norovirus activity was associated with a novel norovirus GII.17 variant in Beijing, China during winter 2014?2015. BMC Infect. Dis. 15, 574. Kim, E.J., Kim, M.S., Chae, Y.Z., and Cheon, D.S. 2012. Prevalence of human noroviruses detected from outbreaks of gastroenteritis patients in Seoul, Korea. Korean J. Microbiol. 48, 102?108. Ko, E.M., Seok, W.S., Lee, T.J., Im, E.J., and Son, S.Y. 2008. Epidemiological characteristics of gastroenteritis outbreaks by norovirus in Gangwon-do 2007. Rep. Inst. Kang-won Health & Environment 19, 30?40.

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UCI(KEPA) : I410-ECN-0101-2018-475-001909717