Physical Characterization and In Vitro Skin Permeation of Elastic Liposomes Loaded with Kaempferol and Nicotiflorin

So Hyun Park; Hyuk Soo Shin; Mid Eum Yun; Sang Lae Lee; Ba Reum Song; Nan Hee Lee; Soo Nam Park

doi:10.7317/pk.2018.42.2.330

Physical Characterization and In Vitro Skin Permeation of Elastic Liposomes Loaded with Kaempferol and Nicotiflorin

Recommendations

Search

Questions

Kaempferol과 Nicotiflorin을 담지한 탄성 리포좀의 물리적 특성 및 In Vitro 피부 투과 연구

Type: Academic journal

Author: So Hyun Park (서울과학기술대학교) Hyuk Soo Shin (서울과학기술대학교) Mid Eum Yun (서울과학기술대학교) Sang Lae Lee (서울과학기술대학교) Ba Reum Song (서울과학기술대학교) Nan Hee Lee (서울과학기술대학교) Soo Nam Park (서울과학기술대학교)

Journal: The Polymer Society Of Korea Polymer Korea Vol.42 No.2 KCI Accredited Journals SCIE

Published: 2018.3

Pages: 330 - 338 (9page)

DOI: 10.7317/pk.2018.42.2.330

Usage

📌

Topic

📖

Background

🔬

Method

🏆

Result

Physical Characterization and In Vitro Skin Permeation of Elastic Liposomes Loaded with Kaempferol and Nicotiflorin

Abstract· Keywords

Report Errors

In this study, kaempferol and nicotiflorin loaded elastic liposomes (ELs) were investigated to enhance the transdermal delivery. The physical properties and in vitro permeation studies were performed using constructed ELs composed of egg phosphatidylcholine (PC) and edge activator (cetearyl glucoside). In kaempferol loaded liposomes, particle size ranged from 121.5 to 157.8 nm, deformability was recorded as 2.8~17.6%, and loading efficiency was from 67.5 to 81.2%. In nicotiflorin loaded liposomes, particle size ranged from 125.1 to 143.1 nm, deformability was recorded as 1.1~17.7%, and loading efficiency was from 52.0 to 66.1%. In vitro skin permeation studies demonstrated that elastic liposomes (ELK3 and ELN3) having 15%(w/w) cetearyl glucoside exhibited the higher skin permeability than CLK and CLN, the conventional liposome without cetearyl glucoside. The findings suggest that EL3 selected as the optimal formulation could be used as useful formulation for transdermal delivery of kaempferol and nicotiflorin.

#elastic liposome #kaempferol #nicotiflorin #transdermal delivery #skin permeation

초록
Abstract
서론
실험
결과 및 토론
결론
참고문헌

References (31)

Add References

[학술지(정기간행물)] - D. Srichana / 2011 / / Southeast Asian J. Trop. Med. Public Health 42 : 704 ~

[학술지(정기간행물)] - G. A. Asare / 2015 / / Integr. Cancer Ther. 14 : 65 ~

[학술지(정기간행물)] - Ismail O. Ishola / 2014 / Mechanisms of Analgesic and Anti-Inflammatory Properties of Annona muricata Linn. (Annonaceae) Fruit Extract in Rodents / Journal of Medicinal Food 17 (12) : 1375 ~ 1382

[학술지(정기간행물)] - V. Garcia-Mediavilla / 2007 / / Eur. J. Pharmacol. 557 : 221 ~

[학술지(정기간행물)] - H. B. Lee / 2010 / / J. Agric. Food Chem. 58 : 4808 ~

Recommendations

It is an article recommended by DBpia according to the article similarity. Check out the related articles!