지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한외과학회 Annals of Surgical Treatment and Research Annals of Surgical Treatment and Research Vol.95 No.2
- 발행연도
- 2018.8
- 수록면
- 94 - 99 (6page)
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초록· 키워드
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Purpose: Although nonerosive and erosive gastroesophageal reflux disease (GERD) have similar symptom severity, nonerosive reflux disease (NERD) is considered a milder type of GERD and gastroenterologists have hesitated to refer these patients for antireflux surgery. The aim of this study was to compare surgical outcomes of antireflux surgery between patients with NERD and erosive reflux disease (ERD).
Methods: Seventy patients met the inclusion criteria of this study among a total of 117 patients who underwent antireflux surgery from November 2012 to October 2017. According to preoperative endoscopy, patients were classified into NERD group (minimal changes or no esophagitis) and ERD group. Clinical characteristics and surgical outcomes were compared between NERD and ERD.
Results: There were 26 patients in NERD group and 44 patients in ERD group. The male:female ratio was higher in the ERD group than in the NERD group (P = 0.044). Preoperative symptoms, response to acid suppressive medication, acid exposure on pH monitoring study, and esophageal manometry results were similar in the 2 groups. Reflux on barium esophagography was more frequently observed in ERD (77.3%) than in NERD (50.0%, P = 0.019). At 6 months after surgery, complete resolution and partial improvement of GERD symptoms were similar in the 2 groups (80.8% and 15.4%, respectively, in NERD vs. 88.6% and 2.3%, respectively, in ERD; P = 0.363).
Conclusion: Laparoscopic Nissen fundoplication is equally beneficial to patients with NERD and ERD. Antireflux surgery should not be avoided for GERD patients without mucosal breaks on endoscopy as the evidence of erosive esophagitis.
Methods: Seventy patients met the inclusion criteria of this study among a total of 117 patients who underwent antireflux surgery from November 2012 to October 2017. According to preoperative endoscopy, patients were classified into NERD group (minimal changes or no esophagitis) and ERD group. Clinical characteristics and surgical outcomes were compared between NERD and ERD.
Results: There were 26 patients in NERD group and 44 patients in ERD group. The male:female ratio was higher in the ERD group than in the NERD group (P = 0.044). Preoperative symptoms, response to acid suppressive medication, acid exposure on pH monitoring study, and esophageal manometry results were similar in the 2 groups. Reflux on barium esophagography was more frequently observed in ERD (77.3%) than in NERD (50.0%, P = 0.019). At 6 months after surgery, complete resolution and partial improvement of GERD symptoms were similar in the 2 groups (80.8% and 15.4%, respectively, in NERD vs. 88.6% and 2.3%, respectively, in ERD; P = 0.363).
Conclusion: Laparoscopic Nissen fundoplication is equally beneficial to patients with NERD and ERD. Antireflux surgery should not be avoided for GERD patients without mucosal breaks on endoscopy as the evidence of erosive esophagitis.
목차
INTRODUCTION
METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (23)
참고문헌 신청
[학술지(정기간행물)] - 정혜경 / 2011 / Epidemiology of Gastroesophageal Reflux Disease in Asia: A Systematic Review / Journal of Neurogastroenterology and Motility (JNM) 17 (1) : 14 ~ 27
[학술지(정기간행물)] - Vakil N / 2006 / The Montreal definition and classification of gastroesophageal reflux disease: a global evidence-based consensus / Am J Gastroenterol 101 : 1900 ~ 1920
[학술지(정기간행물)] - Tiberiu Hershcovici / 2010 / Nonerosive Reflux Disease (NERD) - An Update / Journal of Neurogastroenterology and Motility (JNM) 16 (1) : 8 ~ 21
[학술지(정기간행물)] - Broeders JA / 2010 / Long-term outcome of Nissen fundoplication in non-erosive and erosive gastrooesophageal reflux disease / Br J Surg 97 : 845 ~ 852
[학술지(정기간행물)] - 박중민 / 2017 / Factors predicting outcomes of laparoscopic Nissen fundoplication for gastroesophageal reflux disease: experience at a single institution in Korea / 대한외과학회지 92 (4) : 184 ~ 190
[학술지(정기간행물)] - Vakil N / 2006 / The Montreal definition and classification of gastroesophageal reflux disease: a global evidence-based consensus / Am J Gastroenterol 101 : 1900 ~ 1920
[학술지(정기간행물)] - Tiberiu Hershcovici / 2010 / Nonerosive Reflux Disease (NERD) - An Update / Journal of Neurogastroenterology and Motility (JNM) 16 (1) : 8 ~ 21
[학술지(정기간행물)] - Broeders JA / 2010 / Long-term outcome of Nissen fundoplication in non-erosive and erosive gastrooesophageal reflux disease / Br J Surg 97 : 845 ~ 852
[학술지(정기간행물)] - 박중민 / 2017 / Factors predicting outcomes of laparoscopic Nissen fundoplication for gastroesophageal reflux disease: experience at a single institution in Korea / 대한외과학회지 92 (4) : 184 ~ 190
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UCI(KEPA) : I410-ECN-0101-2018-514-003356247