지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.6
- 수록면
- 349 - 353 (5page)
이용수
초록· 키워드
오류제보하기
Autophagy is the sequential process whereby cell components are degraded, which can occur due to nutrient deprivation. Its regulation has an essential role in many diseases, functioning in both cell survival and cell death. Autophagy starts when mTORC1 is inhibited, resulting in the activation of several complexes to form a cargo that fuses with a lysosome, where it undergoes degradation. In this review, we describe a plant extract that is well known in Korea, namely Korean ginseng extract; we studied how its derivatives and metabolites can regulate autophagy and thus mediate the pathogenesis of certain diseases.
목차
ABSTRACT
1. Introduction
2. Korean ginseng extract and its components
3. Regulation of autophagy by Korean ginseng extract
4. Regulation of autophagy by ginsenoside derivatives
5. Conclusion
References
참고문헌 (58)
참고문헌 신청
Tooze SA / 2014 / Endocytosis and autophagy: exploitation or cooperation? / Cold Spring Harbor Perspect Biol 6:a018358
Maria Cuervo A / 2004 / Autophagy: in sickness and in health / Trends Cell Biol 14:70~77
Lamb CA / 2013 / Endocytosis and autophagy: shared machinery for degradation / BioEssays 35:34~45
Levine B / 2008 / Autophagy in the pathogenesis of disease / Cell 132:27~42
Yang Z / 2009 / An overview of the molecular mechanism of autophagy / Curr Top Microbiol Immunol 335:1~32
Maria Cuervo A / 2004 / Autophagy: in sickness and in health / Trends Cell Biol 14:70~77
Lamb CA / 2013 / Endocytosis and autophagy: shared machinery for degradation / BioEssays 35:34~45
Levine B / 2008 / Autophagy in the pathogenesis of disease / Cell 132:27~42
Yang Z / 2009 / An overview of the molecular mechanism of autophagy / Curr Top Microbiol Immunol 335:1~32
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