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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한소아내분비학회 Annals of Pediatirc Endocrinology & Metabolism Annals of Pediatirc Endocrinology & Metabolism 제20권 제3호
- 발행연도
- 2015.1
- 수록면
- 136 - 142 (7page)
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Purpose: Polycystic ovary syndrome (PCOS) is characterized by hyperandrogenic anovulation in women of reproductive age. We investigated the metabolic effects of lean and overweight adolescents with PCOS.
Methods: Anthropometric measurements and biochemical parameters were evaluated in 49 adolescents with PCOS and 40 age- and body mass index (BMI)- matched controls. We further divided both PCOS and control groups into those having BMI within the normal range of less than 85th percentile and those being overweight and obese with a BMI greater than 85th percentile.
Results: Hemoglobin, gamma-glutamyl transferase (r-GT), total cholesterol, lowdensity lipoprotein-cholesterol and 2-hour postglucose load plasma insulin levels were significantly elevated in the lean PCOS group than in the lean control group. In the overweight/obese PCOS group, hemoglobin and r-GT levels were significantly elevated than in the overweight/obese control group. In the normal weight group, none of the subjects had metabolic syndrome according to the Adult Treatment Panel III criteria, but the incidence of metabolic syndrome in the overweight/obese PCOS group was 8.3% and that in the overweight/obese control group was 6.7%.
Conclusion: PCOS in adolescents causes metabolic abnormalities, underscoring the importance of early diagnosis of PCOS in oligomenorrheic adolescents.
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참고문헌 (21)
참고문헌 신청
Coviello AD / 2006 / Adolescent girls with polycystic ovary syndrome have an increased risk of the metabolic syndrome associated with increasing androgen levels independent o
Dejager S / 2001 / Smaller LDL particle size in women with polycystic ovary syndrome compared to controls / Clin Endocrinol (Oxf) 54 : 455 ~ 462
Diamanti-Kandarakis E / 2007 / Pathophysiology and types of dyslipidemia in PCOS / Trends Endocrinol Metab 18 : 280 ~ 285
Dunaif A. / 1997 / Insulin Resistance and the polycystic ovary syndrome: mechanism and implications for pathogenesis / Endocr Rev 18 : 774 ~ 800
Dunaif A. / 1999 / Insulin action in the polycystic ovary syndrome / Endocrinol Metab Clin North Am 28 : 341 ~ 359
Dejager S / 2001 / Smaller LDL particle size in women with polycystic ovary syndrome compared to controls / Clin Endocrinol (Oxf) 54 : 455 ~ 462
Diamanti-Kandarakis E / 2007 / Pathophysiology and types of dyslipidemia in PCOS / Trends Endocrinol Metab 18 : 280 ~ 285
Dunaif A. / 1997 / Insulin Resistance and the polycystic ovary syndrome: mechanism and implications for pathogenesis / Endocr Rev 18 : 774 ~ 800
Dunaif A. / 1999 / Insulin action in the polycystic ovary syndrome / Endocrinol Metab Clin North Am 28 : 341 ~ 359
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