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자료유형
학술저널
저자정보
저널정보
대한산부인과학회 Obstetrics & Gynecology Science Obstetrics & Gynecology Science 제63권 제1호
발행연도
2020.1
수록면
87 - 93 (7page)

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ObjectiveRecently, the association between periodontal diseases and polycystic ovary syndrome (PCOS) has been established,and it has been revealed that visfatin levels increase in chronic periodontitis (CP) and PCOS. However, there was nostudy comparing the mean visfatin levels between advanced CP and PCOS. Therefore, the probable role of visfatinlinking these diseases remains unknown, and this study was conducted to address this gap. MethodsIn this age- and weight-matched case-control study (cases with PCOS disease and controls without it), 110 femaleparticipants were divided into 4 groups based on clinical findings. The 1st group participants had both PCOS andadvanced CP (n=30), 2nd group participants had only PCOS (n=25), 3rd group participants had only advanced CP (n=23),and 4th group comprised of healthy participants (n=32). Enzyme-linked immunosorbent assay was used to investigatevisfatin levels in the gingival crevicular fluid (GCF). Data were collected and analyzed using Stata software (version11). ResultsThe results revealed the significant effect of both PCOS and advanced CP on visfatin levels in the GCF (P<0.05). ConclusionAccording to the results of this study, the visfatin level in the GCF could be the probable link of association betweenPCOS and advanced CP.

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