지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 175 - 185 (11page)
이용수
초록· 키워드
오류제보하기
Nonsense-mediated mRNA decay (NMD) is a surveillance mechanism ensuring the fast decay of mRNAs harboring a premature termination codon (PTC). As a quality control mechanism, NMD distinguishes PTCs from normal termination codons in order to degrade PTC-carrying mRNAs only. For this, NMD is connected to various other cell processes which regulate or activate it under specific cell conditions or in response to mutations, mis-regulations, stresses, or particular cell programs. These cell processes and their connections with NMD are the focus of this review, which aims both to illustrate the complexity of the NMD mechanism and its regulation and to highlight the cellular consequences of NMD inhibition.
목차
등록된 정보가 없습니다.
참고문헌 (25)
참고문헌 신청
Behm-Ansmant I / 2007 / A conserved role for cytoplasmic poly(A)-binding protein 1(PABPC1)in nonsense-mediated mRNA decay / EMBO J 26 : 1591 ~ 1601
Chang YF / 2007 / The nonsense-mediated decay RNA surveillance pathway / Annu Rev Biochem 76 : 51 ~ 74
Conti E / 2005 / Nonsense-mediated mRNA decay: molecular insights and mechanistic variations across species / Curr Opin Cell Biol 17 : 316 ~ 325
Eberle AB / 2008 / Posttranscriptional gene regulation by spatial rearrangement of the 3' untranslated region / PLoS Biol 6 : e92 ~
Fatscher T / 2015 / Mechanism, factors, and physiological role of nonsense-mediated mRNA decay / Cell Mol Life Sci 72 : 4523 ~ 4544
Chang YF / 2007 / The nonsense-mediated decay RNA surveillance pathway / Annu Rev Biochem 76 : 51 ~ 74
Conti E / 2005 / Nonsense-mediated mRNA decay: molecular insights and mechanistic variations across species / Curr Opin Cell Biol 17 : 316 ~ 325
Eberle AB / 2008 / Posttranscriptional gene regulation by spatial rearrangement of the 3' untranslated region / PLoS Biol 6 : e92 ~
Fatscher T / 2015 / Mechanism, factors, and physiological role of nonsense-mediated mRNA decay / Cell Mol Life Sci 72 : 4523 ~ 4544
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Longevity regulation by NMD-mediated mRNA quality control
BMB Reports
2017 .01
-
A new function of glucocorticoid receptor: regulation of mRNA stability
BMB Reports
2015 .01
-
Translation initiation mediated by nuclear cap-binding protein complex
BMB Reports
2017 .01
-
The Yin and Yang of RNA surveillance in B lymphocytes and antibody-secreting plasma cells
BMB Reports
2019 .01
-
Lentivirus-mediated silencing of the PTC1 and PTC2 genes promotes recovery from spinal cord injury by activating the Hedgehog signaling pathway in a rat model
Experimental and Molecular Medicine
2017 .01
-
Method Development for mRNA Vaccine
한국생물공학회 학술대회
2023 .10
-
Translational control of mRNAs by 3’-Untranslated region binding proteins
BMB Reports
2017 .01
-
YAlO<sub>3</sub>:Tb<sub>x</sub><sup>3+</sup>에서 발광소멸 곡선을 이용한 에너지 전달에 관한 연구
반도체디스플레이기술학회지
2015 .01
-
The emerging role of RNA modi fications in the regulation of mRNA stability
Experimental and Molecular Medicine
2020 .01
-
Improvement of mRNA Stability on a Lysate-based Cell-free System
한국생물공학회 학술대회
2023 .04
-
mRNA Mixed Tailing and Its Implication in mRNA Therapeutic
한국생물공학회 학술대회
2023 .10
-
A Novel mRNA Delivery System Using Self-Assembled Lipid Nanoparticles
한국생물공학회 학술대회
2022 .09
-
Development of RNA Structures for the Development of Cancer Immunotherapeutic Vaccine System
한국고분자학회 학술대회 연구논문 초록집
2021 .04
-
좌우독립 제어 고전압 PTC 히터 개발
한국자동차공학회 추계학술대회 및 전시회
2015 .11
-
Optimization of mRNA Transfection Conditions with Polymeric Nanoparticles on Human Natural Killer Cells
한국생물공학회 학술대회
2021 .10
-
The Studies of mRNA Vaccine
한국생물공학회 학술대회
2020 .06
-
EPANET 2.0과 관망실험을 통한 배수관망 염소농도 감쇄 비교연구
상하수도학회지
2018 .01
-
감쇠계수 등가추적법을 이용한 조류 생장/소멸 수치모의
한국안전학회지
2018 .01
-
퓨즈와 온도특성을 이용한 PTC 센서의 적용방식에 대한 연구
대한전자공학회 학술대회
2015 .06
-
인공지능 기반의 mRNA 백신 디자인 프레임워크
한국정보과학회 학술발표논문집
2023 .06
이 논문의 저자 정보
최근 본 자료
댓글(0)
0