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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 60 - 71 (12page)
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Ba ckground: We conducted a population-based cross-sectional study of Korean adults to evaluate theassociation between metabolic syndrome and microalbuminuria as a marker for early-stage chronickidney disease.
Me thods: A total of 8,497 adults (3,625 men and 4,872 women) who participated in the Korea NationalHealth and Nutrition Examination Survey between 2011 and 2012 were included. Metabolicsyndrome was defined according to recommendation from a joint interim statement of internationalorganizations published in 2009. Microalbuminuria was defined as a urinary albumin-to-creatinineratio of 30 to 300 mg/g. The association between metabolic syndrome and microalbuminuriawas evaluated using logistic regression analysis with adjustment for covariates while consideringsampling weights and the complex survey design.
Re sults: The prevalence of microalbuminuriain subjects with metabolic syndrome was 11% for menand 14.4% for women, whereas the prevalence in subjects without metabolic syndrome was 3.1% formen and 6.7% for women. Metabolic syndrome was significantly associated with an increased risk ofmicroalbuminuriain both women (odds ratio, 2.79; 95% confidence interval, 2.01 to 3.88) and men (oddsratio, 3.00; 95% confidence interval, 2.11 to 4.27). All components of the metabolic syndrome wereassociated with a significantly increased risk of microalbuminuria with the strongest association for highblood pressure. The risk of microalbuminuria increased in a dose-dependent manner (P-value for trend <0.001) with the number of metabolic syndrome components observed for both sexes.
Co nclusion: These findings suggest that metabolic syndrome is a risk factor for chronic kidney diseasefrom an early stage.
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참고문헌 (24)
참고문헌 신청
[학술지(정기간
Alberti KG / 2009 / Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National
Chen J / 2004 / The metabolic syndrome and chronic kidney disease in U.S. adults / Ann Intern Med 140 : 167 ~ 174
Choi HS / 2006 / The relationship of microalbuminuria with metabolic syndrome / Nephron Clin Pract 104 : c85 ~ c93
Galassi A / 2006 / Metabolic syndrome and risk of cardiovascular disease: a meta-analysis / Am J Med 119 : 812 ~ 819
Alberti KG / 2009 / Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National
Chen J / 2004 / The metabolic syndrome and chronic kidney disease in U.S. adults / Ann Intern Med 140 : 167 ~ 174
Choi HS / 2006 / The relationship of microalbuminuria with metabolic syndrome / Nephron Clin Pract 104 : c85 ~ c93
Galassi A / 2006 / Metabolic syndrome and risk of cardiovascular disease: a meta-analysis / Am J Med 119 : 812 ~ 819
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