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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 188 - 196 (9page)
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초록· 키워드
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Background: Metabolic syndrome (MS) is known to increase the risk of various cardiometabolic diseases and insulinresistance (IR) has known to have central role in the development of MS. Many surrogate indices of IR havebeen proposed and the detection of MS might be a suitable model for assessing the accuracy of surrogate indices.
The aims of our study are to invest the most appropriate index by assessment of the diagnostic capacity of IR amongeach surrogate index and identifying cut-off values for discriminating uncomplicated MS in Korean adults.
Methods: A cross-sectional study was performed, assessing 294 Korean adults, 85 of whom were diagnosed withuncomplicated MS. The sensitivities and specificities of five surrogate IR indices were compared to discriminateMS from healthy subjects; these included fasting serum insulin, homeostasis model assessment–insulin resistanceindex, quantitative insulin sensitivity check index, McAuley index, and Disse index. Correlations between each indexvalue were assessed using Pearson’s and Spearman’s correlation methods.
Results: The McAuley index showed the highest area under the curve (0.85), specificity (86.12%), accuracy(82.31%), positive predictive value (68.13%), and negative predictive value (88.67%) to distinguish MS, with a cut-offpoint of 5.3 defined. Correlation coefficients of the five indices showed that the McAuley index had the strongestcorrelation with IR.
Conclusion: The McAuley index showed the best accuracy in the detection of MS as a surrogate marker of IR. Toestablish more effective and accurate standards of measuring IR, comprehensive and multi-scaled studies are required.
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참고문헌 (32)
참고문헌 신청
Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults / 2001 / Executive summary of the third report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) / JAMA 285:2486~2497
Mottillo S / 2010 / The metabolic syndrome and cardiovascular risk a systematic review and meta-analysis / J Am Coll Cardiol 56:1113~1132
Nestel P / 2007 / Metabolic syndrome: recent prevalence in East and Southeast Asian populations / Asia Pac J Clin Nutr 16:362~367
Despres JP / 2006 / Abdominal obesity and metabolic syndrome / Nature 444:881~887
Lim S / 2011 / Increasing prevalence of metabolic syndrome in Korea: the Korean National Health and Nutrition Examination Survey for 1998-2007 / Diabetes Care 34:1323~1328
Mottillo S / 2010 / The metabolic syndrome and cardiovascular risk a systematic review and meta-analysis / J Am Coll Cardiol 56:1113~1132
Nestel P / 2007 / Metabolic syndrome: recent prevalence in East and Southeast Asian populations / Asia Pac J Clin Nutr 16:362~367
Despres JP / 2006 / Abdominal obesity and metabolic syndrome / Nature 444:881~887
Lim S / 2011 / Increasing prevalence of metabolic syndrome in Korea: the Korean National Health and Nutrition Examination Survey for 1998-2007 / Diabetes Care 34:1323~1328
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