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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 103 - 108 (6page)
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Colonization of the pre-transplant lung by multidrug-resistant bacteria affects short- and long-term outcomes of lung transplantation.
However, there are no case reports on the colonization of a pre-transplant lung by drug-resistant Acinetobacter baumannii. We report a case of extensively drug resistant (XDR) A. baumannii colonization in the tracheobronchial tree that caused severe infectious complications after bilateral lung transplantation. A 23-year-old man diagnosed with bronchiolitis obliterans syndrome (BOS) 4 years earlier with a history of allogenic bone marrow transplantation for acute lymphoblastic leukemia was admitted to the hospital with dyspnea. Due to progressive hypercapnic respiratory failure, long-term mechanical ventilation was started after a tracheostomy was performed, and the patient underwent a bilateral lung transplantation to treat end-stage BOS. After the transplantation, the colonization of XDR A. baumannii caused severe bacterial pneumonia in the early postoperative period. Combined treatment with colistin and meropenem led to recovery from the pneumonia but caused drug-induced renal failure. Because many centers are willing to transplant candidates who are on mechanical ventilation or extracorporeal life support, the incidence of XDR A. baumannii colonization of pretransplant lungs is expected to increase. Further studies are needed to examine pre-transplant management strategies in patients colonized with XDR A. baumannii.
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참고문헌 (20)
참고문헌 신청
Bonvillain RW / 2007 / Post-operative infections in cystic fibrosis and non-cystic fibrosis patients after lung transplantation / J Heart Lung transplant 26 : 890 ~ 897
Falagas ME / 2006 / Toxicity of polymyxins: a systematic review of the evidence from old and recent studies / Crit Care 10 : R27 ~
Fournier PE / 2006 / The epidemiology and control of Acinetobacter baumannii in health care facilities / Clin Infect Dis 42 : 692 ~ 699
Gallagher JC / 2008 / Tigecycline for the treatment of Acinetobacter infections: a case series / Ann Pharmacother 42 : 1188 ~ 1194
Gordon NC / 2009 / A review of clinical and microbiological outcomes following treatment of infections involving multidrug-resistant Acinetobacter baumannii with tigecycline
Falagas ME / 2006 / Toxicity of polymyxins: a systematic review of the evidence from old and recent studies / Crit Care 10 : R27 ~
Fournier PE / 2006 / The epidemiology and control of Acinetobacter baumannii in health care facilities / Clin Infect Dis 42 : 692 ~ 699
Gallagher JC / 2008 / Tigecycline for the treatment of Acinetobacter infections: a case series / Ann Pharmacother 42 : 1188 ~ 1194
Gordon NC / 2009 / A review of clinical and microbiological outcomes following treatment of infections involving multidrug-resistant Acinetobacter baumannii with tigecycline
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Factors Associated with Lung Function Recovery at the First Year after Lung Transplantation
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Colistin, Hot Potato for the Therapy of Carbapenem-resistant Acinetobacter baumannii infections
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Abrupt Increase in Rate of Imipenem Resistance in Acinetobacter baumannii Complex Strains Isolated from General Hospitals in Korea and Correlation With Carbapenem Administration During 2002–2013
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