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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한소아알레르기호흡기학회 Allergy Asthma & Respiratory Diseases Allergy Asthma & Respiratory Diseases 제3권 제4호
- 발행연도
- 2015.1
- 수록면
- 307 - 309 (3page)
이용수
초록· 키워드
오류제보하기
Polyethylene glycol (PEG) 3350 is the main ingredient of oral solutions for bowel preparation prior to colonoscopy. This high-molecular-weight PEG has shown a low incidence of adverse reactions because of its low absorption via the intestine. Systemic allergic reactions to PEG solution are very rare, and only 10 cases have been reported in the literature worldwide. We experienced a case of immediate hypersensitivity reaction to PEG 3350. A 35-year-old male patient was prescribed PEG 3350 solution for colonoscopy. After ingestion of 2.5 pack (55 g of PEG 3350 powder), he began to show urticaria on both arms and trunk, and swelling in the lips. Symptoms resolved over the next few hours without any treatment. Skin prick and intradermal tests with PEG 3350 showed positive responses to both test. We also performed oral provocation tests with PEG 3350. Thirty minutes after ingestion of 2.5 g of PEG 3350 powder, the patient presented with mild urticaria and angioedema. Finally he was diagnosed with immediate hypersensitivity reaction by PEG 3350. The patient underwent colonoscopy after preparation with sodium phosphate solution without any adverse reactions. We herein report the first case of PEG 3350-induced immediate hypersensitivity reaction confirmed by skin and oral provocation tests in Korea.
목차
등록된 정보가 없습니다.
참고문헌 (15)
참고문헌 신청
Marshall JB / 1993 / Prospective, randomized trial comparing sodium phosphate solution with polyethylene glycol-electrolyte lavage for colonoscopy preparation / Gastrointest Endosc 39:631~634
Brady CE 3rd / 1986 / Urinary excretion of polyethylene glycol 3350 and sulfate after gut lavage with a polyethylene glycol electrolyte lavage solution / Gastroenterology 90:1914~1918
Schuman E / 1991 / Probable anaphylactic reaction to polyethylene glycol electrolyte lavage solution / Gastrointest Endosc 37:411
Brullet E / 1992 / Urticarial reaction to oral polyethylene glycol electrolyte lavage solution / Gastrointest Endosc 38:400~401
Stollman N / 1996 / Angioedema from oral polyethylene glycol electrolyte lavage solution / Gastrointest Endosc 44:209~210
Brady CE 3rd / 1986 / Urinary excretion of polyethylene glycol 3350 and sulfate after gut lavage with a polyethylene glycol electrolyte lavage solution / Gastroenterology 90:1914~1918
Schuman E / 1991 / Probable anaphylactic reaction to polyethylene glycol electrolyte lavage solution / Gastrointest Endosc 37:411
Brullet E / 1992 / Urticarial reaction to oral polyethylene glycol electrolyte lavage solution / Gastrointest Endosc 38:400~401
Stollman N / 1996 / Angioedema from oral polyethylene glycol electrolyte lavage solution / Gastrointest Endosc 44:209~210
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