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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 26 - 31 (6page)
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초록· 키워드
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Background and Purpose Despite the successful use of a ketogenic diet in pediatric epilepsy, its application in adults has been limited. The aim of this meta-analysis was to summarize thefindings of relevant published studies in order to identify the efficacy of and compliance with aketogenic diet and its main subtypes (i.e., classic ketogenic diet and modified Atkins diet) inadults with intractable epilepsy, and to provide useful information for clinical practice.
Methods Electronic searches of PubMed, EMBASE, Google Scholar, and the ISI Web of Science were conducted to identify studies of the efficacy of and patient compliance with a ketogenic diet in adults with intractable epilepsy; the included studies were reviewed. Meta-analyseswere performed using STATA to determine combined efficacy rates and combined rates of compliance with the ketogenic diet and its main subtypes.
Results In total, 12 studies qualified for inclusion, and data from 270 patients were evaluated.
The results of the meta-analysis revealed combined efficacy rates of all types of ketogenic diet,a classical ketogenic diet, and a modified Atkins diet were 42%, 52%, and 34%, respectively;the corresponding combined compliance rates were 45%, 38%, and 56%.
Conclusions The results indicate that a ketogenic diet is a promising complementary therapyin adult intractable epilepsy, and that while a classical ketogenic diet may be more effective,adult patients are likely to be less compliant with it than with a modified Atkins diet.
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참고문헌 (24)
참고문헌 신청
Auvin S / 2012 / Should we routinely use modified Atkins diet instead of regular ketogenic diet to treat children with epilepsy? / Seizure 21 : 237 ~ 240
Barborka CJ / 1930 / Epilepsy in adults: results of treatment by ketogenic diet in one hundred cases / Arch Neurol Psychiatry 23 : 904 ~ 914
Carrette E / 2008 / A pilot trial with modified Atkins’ diet in adult patients with refractory epilepsy / Clin Neurol Neurosurg 110 : 797 ~ 803
Cervenka MC / 2012 / E-mail management of the modified Atkins Diet for adults with epilepsy is feasible and effective / Epilepsia 53 : 728 ~ 732
Cervenka MC / 2013 / Dietary treatment of intractable epilepsy / Continuum (Minneap Minn) 19 (3) : 756 ~ 766
Barborka CJ / 1930 / Epilepsy in adults: results of treatment by ketogenic diet in one hundred cases / Arch Neurol Psychiatry 23 : 904 ~ 914
Carrette E / 2008 / A pilot trial with modified Atkins’ diet in adult patients with refractory epilepsy / Clin Neurol Neurosurg 110 : 797 ~ 803
Cervenka MC / 2012 / E-mail management of the modified Atkins Diet for adults with epilepsy is feasible and effective / Epilepsia 53 : 728 ~ 732
Cervenka MC / 2013 / Dietary treatment of intractable epilepsy / Continuum (Minneap Minn) 19 (3) : 756 ~ 766
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