지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2002.1
- 수록면
- 58 - 61 (4page)
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초록· 키워드
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Purpose: In order to evaluate the response to radiation
therapy and to analyze the patterns of failure, survival
and complications, we performed a retrospective analysis
of patients with conjunctival lymphoma.
Materials and Methods: From November 1991 to March
1999, 11 patients were diagnosed as conjunctival lymphoma
at Asan Medical Center. Five patients had bilateral
involvements, and a total of 16 eyes received radiation
therapy. Using 6 to 9 MeV electrons or 4 MV photon
beams, all patients were treated with a single anterior
field to total doses ranging from 30 Gy to 45 Gy delivered
in 10 to 25 fractions. The median follow up period was
57 Months.
Results: All patients achieved a complete response
with radiation therapy. Two of 16 eyes that were treated
(12.5%) developed local recurrence after radiation therapy,
however they were salvaged with 30 Gy of reirradiation.
The five-year local control was 88.9%. One out of
11 patients (9.9%) developed lung metastasis and received
chest irradiation. At the last follow up, one had died of
pneumonia and 10 patients were alive without disease
evidence. The five-year overall survival rate was 77.8%
and 5-year disease free survival was 77.8%. Cataract and
dry eye occurred in one patient (9.9%) respectively.
Conclusion: Radiation therapy is a very effective and
safe treatment modality for conjunctival lymphoma. The
local control rate of radiotherapy was excellent and
complications were acceptable. Radiation therapy is also
an effective treatment modality for recurrent conjunctival
lymphoma. It generally requires more than three months
to achieve complete response following radiation therapy,
thus we recommend evaluating the response to radiation
therapy at three months after completion of treatment.
(Cancer Res Treat. 2002;34:58-61)
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