지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 494 - 501 (8page)
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초록· 키워드
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Purpose Malignant central nervous system (CNS) germ cell tumors (GCTs), although rare, are thought to occur more frequently among Asians. However, a recent population-based study revealed no differences in GCT incidence between Asians and Caucasians. Therefore, this study was conducted to determine the incidence and survival rates of CNS GCTs using the national cancer incidence database, and to compare these rates to those in the United States and Japan.
Materials and Methods We extracted CNS GCT patients diagnosed between 2005 and 2012 from the Korea Central Cancer Registry database. Age-standardized rates (ASRs), annual percentage change, and the male-female incidence rate ratios (IRRs) were calculated. To estimate the survival rate, we used data for patients diagnosed between 2005 and 2010 and followed their cases until December 31, 2013.
Results The ASR for CNS GCT between 2005 and 2012 was 0.179 per 100,000 (95% confidence interval, 0.166 to 0.193), with an overall male-to-female (M:F) IRR of 2.95:1. However, when stratified by site, the M:F IRR was 13.62:1 for tumors of the pineal region and 1.87:1 for those located in nonpineal regions. The most frequent histologic type was germinoma (76.0%), and the most frequent location was the suprasellar region (48.5%). The 5-year survival rate of germinoma patients was 95.3%.
Conclusion The incidence rate of CNS GCTs in Korea during 2005-2012 was 0.179 per 100,000, which was similar to that of the Asian/Pacific Islander subpopulation in the United States. Moreover, the CNS GCT survival rate in Korea was similar to rates in Japan and the United States.
목차
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참고문헌 (23)
참고문헌 신청
Bailey S / 1996 / Pineal tumours in the north of England 1968-93 / Arch Dis Child 75 : 181 ~ 185
Cho KT / 2002 / Pediatric brain tumors : statistics of SNUH, Korea(1959-2000) / Childs Nerv Syst 18 : 30 ~ 37
Goodwin TL / 2009 / Incidence patterns of central nervous system germ cell tumors : a SEER Study / J Pediatr Hematol Oncol 31 : 541 ~ 544
Hai-Rim Shin / 2005 / Nationwide Cancer Incidence in Korea, 1999~2001; First Result Using the National Cancer Incidence Database / Cancer Research and Treatment 37 (6) : 325
Kaatsch P / 2001 / Population-based epidemiologic data on brain tumors in German children / Cancer 92 : 3155 ~ 3164
Cho KT / 2002 / Pediatric brain tumors : statistics of SNUH, Korea(1959-2000) / Childs Nerv Syst 18 : 30 ~ 37
Goodwin TL / 2009 / Incidence patterns of central nervous system germ cell tumors : a SEER Study / J Pediatr Hematol Oncol 31 : 541 ~ 544
Hai-Rim Shin / 2005 / Nationwide Cancer Incidence in Korea, 1999~2001; First Result Using the National Cancer Incidence Database / Cancer Research and Treatment 37 (6) : 325
Kaatsch P / 2001 / Population-based epidemiologic data on brain tumors in German children / Cancer 92 : 3155 ~ 3164
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