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학술저널
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대한진단검사의학회 Annals of Laboratory Medicine Annals of Laboratory Medicine 제36권 제3호
발행연도
2016.1
수록면
278 - 280 (3page)

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Dear Editor, Herein, we report the first case of human infection with Ochrobactrum tritici, primarily isolated from environmental sources and not previously known to infect humans. A 70-yr-old male patient was admitted to a tertiary-care hospital for jaundice. He had a medical history of cholangiocellular carcinoma (CCC). On the first day of hospitalization, he presented a 38.1°C body temperature, 98/81 mmHg blood pressure, 87 beats per minute heart rate, and abdominal distention. Laboratory findings indicated a white blood cell count of 5.63×109/L with a differential of 71% neutrophils, a hemoglobin level of 10 g/dL, a platelet count of 25×109/L, and a C-reactive protein level of 48.5 mg/L (reference range, 0.1-6.0 mg/L). Two sets of blood cultures were performed at the time of high fever on admission. Among these four cultures, only one aerobic culture was positive for gram-negative short rods after 4 days of incubation. Intravenous antibiotics with metronidazole (500 mg every 8 hr) and cefoperazone/sulbactam (2,000 mg every 12 hr) were started on the first day of hospitalization. His condition improved after antibiotic therapy and he was discharged from the hospital on day five. The isolate (named GNOT01) was identified as Ochrobactrum anthropi by matrix-assisted laser desorption ionization–time of flight mass spectrometer (MALDI-TOF MS; MicroFlex LT, Bruker Daltonics, Bremen, Germany).

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