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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 378 - 380 (3page)
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Dear Editor, Carbapenem-resistant Enterobacteriaceae have acquired carbapenemase genes [1], which differ substantially across countries [2]. Transferable carbapenemase IMP-type metallo-β-lactamases, particularly IMP-1 and IMP-6, are commonly identified in the clinical setting in Japan [3, 4] and exhibit different substrate specificity despite having a difference of only one amino acid (IMP-6: Ser214Gly). IMP-1 producers are more resistant to imipenem than to meropenem, whereas IMP-6 producers are more resistant to meropenem [5]. We previously found that the susceptibility rate of IMP-6-positive Escherichia coli was higher for imipenem than for meropenem [3]. Thus, IMP-6-producing isolates may be erroneously categorized as imipenem-susceptible, which could lead to treatment failure in patients.
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참고문헌 (9)
참고문헌 신청
Gupta N / 2011 / Carbapenem-resistant Enterobacteriaceae: epidemiology and prevention / Clin Infect Dis 53:60~67
Nordmann P / 2011 / Global spread of carbapenemase-producing Enterobacteriaceae / Emerg Infect Dis 17:1791~1798
Yano H / 2012 / High frequency of IMP-6 among clinical isolates of metallo-${\beta}$ -lactamaseproducing Escherichia coli in Japan / Antimicrob Agents Chemother 56:4554~4555
Saito K / 2017 / Suitability of carbapenem inactivation method (CIM) for detection of IMP metallo-${\beta}$ -lactamase-producing Enterobacteriaceae / J Clin Microbiol 55:1220~1222
Yano H / 2001 / Plasmid-encoded metallo-${\beta}$ -lactamase (IMP-6) conferring resistance to carbapenems, especially meropenem / Antimicrob Agents Chemother 45:1343~1348
Nordmann P / 2011 / Global spread of carbapenemase-producing Enterobacteriaceae / Emerg Infect Dis 17:1791~1798
Yano H / 2012 / High frequency of IMP-6 among clinical isolates of metallo-
Saito K / 2017 / Suitability of carbapenem inactivation method (CIM) for detection of IMP metallo-
Yano H / 2001 / Plasmid-encoded metallo-
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