지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 120 - 125 (6page)
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초록· 키워드
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Objective To investigate the correlation between depressive symptoms and serum vitamin D levels in stroke patients.Methods In total, 126 stroke patients were analyzed. The 25-hydroxyvitamin D (25-OHD) concentration of each patient was used to determine their vitamin D status. Depressive symptoms were assessed using the Beck Depression Inventory II (BDI-II) and the Patient Health Questionnaire 9 (PHQ-9). Functional status was evaluated with the Korean version of the Modified Barthel Index (K-MBI). We compared the clinical questionnaires of a vitamin D-deficient group and a normal group, and evaluated the correlations between BDI-II, PHQ-9, K-MBI, and serum 25-OHD levels.Results In the vitamin D-deficient group, BDI-II (16.0±12.1) and PHQ-9 (7.4±4.2) scores were significantly higher than those of the normal group (BDI-II, 9.1±7.2; PHQ-9, 4.2±2.9; p<0.01). In a Spearman correlation analysis, a significant negative correlation was found between serum 25-OHD levels and BDI-II (Spearman r=0.177, p=0.048), but there were no significant correlations between serum 25-OHD levels and PHQ-9 or K-MBI. Conclusion Vitamin D deficiency was correlated with the symptoms of depression in stroke patients.
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참고문헌 (32)
참고문헌 신청
Hackett ML / 2005 / Frequency of depression after stroke: a systematic review of observational studies / Stroke 36:1330~1340
Gillen R / 2001 / Depressive symptoms and history of depression predict rehabilitation efficiency in stroke patients / Arch Phys Med Rehabil 82:1645~1649
Wei N / 2015 / Post-stroke depression and lesion location: a systematic review / J Neurol 262:81~90
Krishnan V / 2010 / Linking molecules to mood:new insight into the biology of depression / Am J Psychiatry 167:1305~1320
Holick MF / 2007 / Vitamin D deficiency / N Engl J Med 357:266~281
Gillen R / 2001 / Depressive symptoms and history of depression predict rehabilitation efficiency in stroke patients / Arch Phys Med Rehabil 82:1645~1649
Wei N / 2015 / Post-stroke depression and lesion location: a systematic review / J Neurol 262:81~90
Krishnan V / 2010 / Linking molecules to mood:new insight into the biology of depression / Am J Psychiatry 167:1305~1320
Holick MF / 2007 / Vitamin D deficiency / N Engl J Med 357:266~281
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