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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한정신약물학회 Clinical Psychopharmacology and Neuroscience Clinical Psychopharmacology and Neuroscience 제14권 제2호
- 발행연도
- 2016.1
- 수록면
- 148 - 152 (5page)
이용수
초록· 키워드
오류제보하기
Objective: The ratio of 2nd to 4th digit length (2D:4D) is a sexually dimorphic trait. Men have a relatively shorter second digit than fourth digit. This ratio is thought to be influenced by higher prenatal testosterone level or greater sensitivity to androgen.
The purpose of this study is to investigate the relationship between alcohol dependence and 2D:4D in a Korean sample and whether 2D:4D can be a biologic marker in alcohol dependence.
Methods: In this study, we recruited 87 male patients with alcohol dependence from the alcohol center of one psychiatric hospital and 52 healthy male volunteers who were all employees in the same hospital as controls. We captured images of the right and left hands of patients and controls using a scanner and extracted data with a graphics program. We measured the 2D:4D of each hand and compared the alcohol dependence group with the control group. We analyzed these ratios using an independent-samples t-test.
Results: The mean 2D:4D of patients was 0.934 (right hand) and 0.942 (left hand), while the mean 2D:4D of controls was 0.956 (right hand) and 0.958 (left hand). Values for both hands were significantly lower for patients than controls (p＜0.001, right hand; p=0.004, left hand).
Conclusion: Patients who are alcohol dependent have a significantly lower 2D:4D than controls, similar to the results of previous studies, which suggest that a higher prenatal testosterone level in the gonadal period is related to alcoholism. Furthermore, 2D:4D is a possible predictive marker of alcohol dependence.
목차
등록된 정보가 없습니다.
참고문헌 (37)
참고문헌 신청
Lee HK / 2010 / The prevalence and correlates of alcohol use disorders in the United States and Korea--a cross-national comparative study / Alcohol 44:297~306
Association AP / 2000 / DSM-IV-TR: Diagnostic and statistical manual of mental disorder / American Psychiatric Publishing
von Knorring AL / 1985 / Platelet MAO activity as a biological marker in subgroups of alcoholism / Acta Psychiatr Scand 72:51~58
Zilberman M / 2003 / Gender similarities and differences: the prevalence and course of alcohol- and other substance-related disorders / J Addict Dis 22:61~74
Oreland L / 2004 / Platelet monoamine oxidase, personality and alcoholism:the rise, fall and resurrection / Neurotoxicology 25:79~89
Association AP / 2000 / DSM-IV-TR: Diagnostic and statistical manual of mental disorder / American Psychiatric Publishing
von Knorring AL / 1985 / Platelet MAO activity as a biological marker in subgroups of alcoholism / Acta Psychiatr Scand 72:51~58
Zilberman M / 2003 / Gender similarities and differences: the prevalence and course of alcohol- and other substance-related disorders / J Addict Dis 22:61~74
Oreland L / 2004 / Platelet monoamine oxidase, personality and alcoholism:the rise, fall and resurrection / Neurotoxicology 25:79~89
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