지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한정신약물학회 Clinical Psychopharmacology and Neuroscience Clinical Psychopharmacology and Neuroscience 제16권 제1호
- 발행연도
- 2018.1
- 수록면
- 46 - 56 (11page)
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초록· 키워드
오류제보하기
Objective: Reduced hippocampal volume and alterations in white matter tracts have been frequently reported in adults having the history of emotional maltreatment. We investigated whether these structural change occur in adolescents with previous verbal abuse (VA) experiences. Methods: Hippocampal subfield volume and white matter structural connectivity measures were assessed in 31 first year male high school students with various degrees of exposure to parental and peer VA. Results: The high VA group showed significant volume reduction in the left cornu ammonis (CA) 1 and left subiculum compared to the low VA group (p＜0.05). Volumes of left hippocampal subfields CA1 and subiculum were negatively correlated with previous VA experiences (p＜0.05). Increased mean diffusivity (MD) of the splenium of the corpus callosum was related to high VA score across all subjects (p＜0.05). There was an inverse relationship between volume of the CA1 and subiculum and MD of the splenium (p＜0.05). Conclusion: Exposure to parental and peer VA may affect development of the left hippocampal subfields and the splenium of corpus callosum. These structural alterations can be discernible during adolescence.
목차
등록된 정보가 없습니다.
참고문헌 (93)
참고문헌 신청
Green JG / 2010 / Childhood adversities and adult psychiatric disorders in the national comorbidity survey replication I: associations with first onset of DSM-IV disorders / Arch Gen Psychiatry 67:113~123
Vachon DD / 2015 / Assessment of the harmful psychiatric and behavioral effects of different forms of child maltreatment / JAMA Psychiatry 72:1135~1142
Bremner JD / 1997 / Magnetic resonance imaging-based measurement of hippocampal volume in posttraumatic stress disorder related to childhood physical and sexual abuse--a preliminary report / Biol Psychiatry 41:23~32
Vythilingam M / 2002 / Childhood trauma associated with smaller hippocampal volume in women with major depression / Am J Psychiatry 159:2072~2080
Weniger G / 2009 / Reduced amygdala and hippocampus size in trauma-exposed women with borderline personality disorder and without posttraumatic stress disorder / J Psychiatry Neurosci 34:383~388
Vachon DD / 2015 / Assessment of the harmful psychiatric and behavioral effects of different forms of child maltreatment / JAMA Psychiatry 72:1135~1142
Bremner JD / 1997 / Magnetic resonance imaging-based measurement of hippocampal volume in posttraumatic stress disorder related to childhood physical and sexual abuse--a preliminary report / Biol Psychiatry 41:23~32
Vythilingam M / 2002 / Childhood trauma associated with smaller hippocampal volume in women with major depression / Am J Psychiatry 159:2072~2080
Weniger G / 2009 / Reduced amygdala and hippocampus size in trauma-exposed women with borderline personality disorder and without posttraumatic stress disorder / J Psychiatry Neurosci 34:383~388
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