지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한정신약물학회 Clinical Psychopharmacology and Neuroscience Clinical Psychopharmacology and Neuroscience 제6권 제2호
- 발행연도
- 2008.1
- 수록면
- 75 - 78 (4page)
이용수
초록· 키워드
오류제보하기
Tardive dyskinesia (TD) is a serious neurological side effect of antipsychotics. Dopaminergic hypersensitivity mediated by the upregulationof the D2 receptor with prolonged dopamine blockade is thought to play a key role in the development of neurolepticinducedTD. Aripiprazole, a partial dopamine agonist, causes little dopamine up-regulation; therefore, it may be associated witha lower risk of TD. We present a literature review and a case in which a schizophrenic patient developed TD while using longactinginjectable risperidone, which was completely resolved following a switch to aripiprazole. The resolution of TD in this patientwas sustained during 22 months of follow-up treatment with aripiprazole. Aripiprazole may be an effective treatment option forpatients who suffer from neuroleptic-induced TD.
목차
등록된 정보가 없습니다.
참고문헌 (20)
참고문헌 신청
American Psychiatric Association / 1994 / Diagnostic and Statistical Manual of Mental Disorders, 4th ed / American Psychiatric Press Inc
Duggal HS / 2003 / Aripiprazole-induced improvement in tardive dyskinesia / Can J Psychiatry 48 : 771 ~ 772
Eerdekens M / 2004 / Pharmacokinetics and tolerability of long-acting risperidone in schizophrenia / Schizophr Res 70 : 91 ~ 100
Gharabawi GM / 2005 / An assessment of emergent tardive dyskinesia and existing dyskinesia in patients receiving long-acting, injectable risperidone: results from a long-ter
Grant MJ / 2005 / Possible improvement of neurolepticassociated tardive dyskinesia during treatment with aripiprazole / Ann Pharmacother 39 : 1953 ~
Duggal HS / 2003 / Aripiprazole-induced improvement in tardive dyskinesia / Can J Psychiatry 48 : 771 ~ 772
Eerdekens M / 2004 / Pharmacokinetics and tolerability of long-acting risperidone in schizophrenia / Schizophr Res 70 : 91 ~ 100
Gharabawi GM / 2005 / An assessment of emergent tardive dyskinesia and existing dyskinesia in patients receiving long-acting, injectable risperidone: results from a long-ter
Grant MJ / 2005 / Possible improvement of neurolepticassociated tardive dyskinesia during treatment with aripiprazole / Ann Pharmacother 39 : 1953 ~
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