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학술저널
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대한치주과학회 Journal of Periodontal & Implant Science Journal of Periodontal & Implant Science 제39권 제3호
발행연도
2009.1
수록면
349 - 358 (10page)

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Purpose: This study was aimed to evaluate the effect of the Freeze Dried Bone Allograft and Demineralized Bone Matrix on osseous regeneration in the rat calvarial defects. Methods: Eight mm critical-sized calvarial defects were created in the 80 male Sprague-Dawley rats. The animals were divided into 4 groups of 20 animals each. The defects were treated with Freeze Dried Bone Allograft(SureOss ™ ), Demineralized Bone Matrix(ExFuse ™ Gel, ExFuse ™ Putty), or were left untreated for sham-surgery control and were evaluated by histologic and histomorphometric parameters following a 2 and 8 week healing intervals. Statistical analysis was done between each groups and time intervals with ANOVA and paired t-test. Results: Defect closure, New bone area, Augmented area in the SureOss ™ , ExFuse ™ Gel, ExFuse ™ Putty groups were significantly greater than in the sham-surgery control group at each healing interval(P < 0.05). In the New bone area and Defect closure, there were no significant difference between experimental groups. Augmented area in the ExFuse ™ Gel, ExFuse ™ Putty groups were significantly greater than SureOss ™ group at 2weeks(P < 0.05), however there was no significant difference at 8 weeks. Conclusions: All of SureOss ™ , ExFuse ™ Gel, ExFuse ™ Putty groups showed significant new bone formation and augmentation in the calvarial defect model. (J Korean Acad Periodontol 2009;39:349-358)

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