신부전 환자에서 혈액투석이 후각인지기능에 미치는 영향

김진국; 신석균; 임채형; 조영일; 남태욱

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자료유형: 학술저널

저자정보: 김진국 신석균 임채형 조영일 남태욱

저널정보: 대한이비인후과학회 대한이비인후-두경부외과학회지 대한이비인후과학회지 두경부외과학 제45권 제10호

발행연도: 2002.1

수록면: 975 - 979 (5page)

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Background and Objectives：The sense of smell plays an important role in the quality of life. Loss of smell is common in the elderly and it results from respiratory diseases, certain disease states (Alzheimer disease, chronic renal failure (CRF), multiple sclerosis), medications, and surgical interventions. Many studies have shown a declining odor perception in the CRF patients. The objectives of the present study were to test odor identification ability in patients with CRF and the effect of hemodialysis on olfactory recognition, and to examine the possible correlations between smell identification test score and various clinical parameters. Materials and Method：We performed a case-control study comparing the Cross- Cultural Smell Identification Test (CC-SIT) scores of CRF patients with hemodialysis, and those without hemodialysis, and age-sex matched healthy controls. Results：Healthy controls had significantly high CC-SIT scores compared to those of CRF patients without hemodialysis. No significant differences were observed in the CC-SIT scores between CRF patients with hemodialysis and healthy controls and in CRF patients before and after the hemodialysis session. No significant positive correlation was found between CC-SIT score and creatinine clearance in the dialysis group. Conclusion：Acute removal of uremic toxins by hemodialysis does not correct olfactory disturbances. Odor perception is severly impaired in patients with CRF and is related to the degree of renal impairment. (Korean J Otolaryngol 2002;45:975-9)

#만성신부전증·혈액투석·후각인지기능. #Smel· Renal dialysis· Kidney· Failure #chronic.

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