초음파검사에서 발견된 갑상선 결절내석회화소견의 암종에 대한 상대적 위험성

양윤수; 김연우; 오정기; 임현실; 홍기환

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자료유형: 학술저널

저자정보: 양윤수 김연우 오정기 임현실 홍기환

저널정보: 대한이비인후과학회 대한이비인후-두경부외과학회지 대한이비인후과학회지 두경부외과학 제47권 제5호

발행연도: 2004.1

수록면: 457 - 461 (5page)

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Background and Objectives：The aim of this retrospective study was to evaluate the significance of sonographically detected thyroid calcifications in the diagnosis of thyroid cancer. Subjects and Method：Two hundred ninety-one patients with thyroid disease, including 75 with thyroid cancer and 54 with calcified thyroid nodule, were reviewed during the period of January 2001 to May 2003. Each patient underwent preoperative high resolution sonography to evaluate the thyroid gland for the presence of calcifications. Results：The highest incidence of calcification was found in thyroid cancer (36%), followed by multinodular goiter (20%), follicular adenoma (13%), and single nodular goiter (3%). The incidence of cancer was significantly higher in calcified nodules (50%) than in noncalcified nodules in the entire group (20%) (p<0.001), with a relative risk of 3.9. In the group of solitary thyroid nodules, the incidence of cancer in the calcified nodules (56%) was higher than that in the nodules without calcification (21%) (p=0.002). In the group of multiple thyroid nodules, the incidence of cancer in the calcified nodules (47%) was higher than that in the nodules without calcification (19%) (p=0.001). The relative risk in presence of calcification was 4.6 in the solitary nodules and 3.7 in the multiple nodules. Compared with multiple noncalcified thyroid nodules, the solitary calcified nodules demonstrated a relative risk of 5.2. In patients younger and older than 40 years, the relative risk in the presence of calcification was about the same, around 4. Conclusion：The detection of thyroid calcifications by sonography is diagnostically valuable. The presence of calcifications should raise the suspicion of malignancy.

#초음파검사·결절내석회화·갑상선암·비교위험도. #Ultrasonography· Calcification· Thyroid neoplasms· Risk.

참고문헌 (18)

참고문헌 신청

/ 1958 / Calcification in papillary carcinoma of the thyroid 90 : 997 ~ 1000

/ 1968 / Birefringent crystals in humanthyroid 58 : 172 ~ 176

/ 1968 / Soft tissue roentgenography of thyroidnodules 102 : 844 ~ 852

/ 1981 / Radiological patterns and significance of thyroid calcification 32 : 571 ~ 575

/ 1984 / Thyroid nodules:Sonographic-pathologic correlation 151 : 741 ~ 745

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