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논문 기본 정보

자료유형
학술저널
저자정보
저널정보
대한이비인후과학회 대한이비인후-두경부외과학회지 대한이비인후과학회지 두경부외과학 제45권 제4호
발행연도
2002.1
수록면
341 - 347 (7page)

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Background and Objectives:Although sinusitis is comonly caused by nasal diseases that interfere with ostiomeatal unit, whether non-rhinogenic sinusitis afects the function and morphology of the nasal mucosa. The aim of the current study is to observe efects of experimentaly induced maxillary sinusitis on ciliary beat frequency and histopathology of the nasal mucosa in rabbits. Materials and Method:Maxillary sinusitis was induced in the right sides of 10 rabits by partially occluding the natural ostia and inoculating the maxillary sinus with P. aeruginosa. After 4 weeks, the nasal mucosa was obtained from the inferior turbinate and the septum in the right (experimental group) and the left side (control group A). Both sides of the nasal mucosa in another 5 normal rabbits were used as the control group B. Ciliary beat frequency (CBF) was measured by video-computerized analysis and degre of inflammation in histopathology was graded using a 100-point scale of inflammation score. CBF and inflammation score were compared betwen the thre groups. Results:CBFs of the experimental group were higher than those of the control groups. In the experimental group, there were no correlations betwen CBFs of the maxillary and nasal mucosa, but weak corelations existed between inflammation scores of the maxillary and nasal mucosa. Conclusion:Primary maxillary sinusitis can locally induce dysfunction and inflamation of the nasal mucosa. (Korean J Otolaryngol 2002;45:341-7)

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